Protein Alignment uif and clec-17

DIOPT Version :10

• Sequence 1: NP_001162899.1
• Gene: uif / 33983
• FlyBaseID: FBgn0031879
• Length: 3589
• Species: Drosophila melanogaster
• Sequence 2: NP_493152.1
• Gene: clec-17 / 173111
• WormBaseID: WBGene00008477
• Length: 416
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 116/564 - (20%)
• Similarity: 184/564 - (32%)
• Gaps: 189/564 - (33%)

  Fly    18 SLLLLNLLHLIGADEAFSCPNGWELRGLNCYKYFNIKHSWDKSAELCRRYGAELVAIDSYAENNE 82
            :||||.:......:....|.||:.|....|.|.|:.|.:...:...|..:||.||.:.:..:...
 Worm     6 ALLLLIICFKACLNSPLICTNGFTLLNKKCLKLFDTKVNHTSAESSCNSFGATLVTVKNVNDEQA 70

  Fly    83 TLAIARASDPNQRASDKYWLGLASLDDLRTNTLESASGALISQYSGYWSLHQPNAESGECV---- 143
            ...:..||     ::...||||...|......|...:......|..: |:..|..::|.||
 Worm    71 IATVVAAS-----SARLIWLGLYCFDSDPAKCLWDDNSGSAQSYDNF-SIDFPLVDAGHCVYLST 129

  Fly   144 AAAFAGKSQSWDLGTCES-LLPFMC-----RAQACPQGSLHCANGKCINQAFKCD----GSDDCG 198
            ..|.|||   |....||| |:.::|     .|..|    .:..||.|...:...:    ....|.
 Worm   130 LGALAGK---WISEDCESKLMSYICELPTTHADDC----TYNYNGYCYTFSSTAEPFIIAQTKCA 187

  Fly   199 DGTDELDCPAQCHYHMQSGGDVIET---PNYPHKYGA----------LSKCKWTLEGPLGSNIIL 250
            :...:|     ...|..:....|||   .:| :..||          |.|.||
 Worm   188 ETYGDL-----VSIHSSNENRYIETFAAQDY-YLIGAVWKLDNSLYWLDKSKW------------ 234

  Fly   251 QFQDFETEKTFDTVQILVGGRTEDKSVSLATLSGKQDLTTQPFVSASNFMIVKFTTDGSVERKGF 315
            .:.:.:.|.::          ..|..|:::|      :.:.|..|                  ||
 Worm   235 DYNNTDPENSY----------RGDYCVAMST------VISSPIPS------------------GF 265

  Fly   316 RATWKTEAKNCGGTLKATLQRQILTSPNYPKQYPGGLECLYVIKAQPGRIISIEVDDLDIADGRD 380
               |  .:.||....|...:|            |.|::
 Worm   266 ---W--FSTNCTRPAKYICKR------------PAGVQ--------------------------- 286

  Fly   381 FLMIRDGESPMSRTIAKLTGKTAQNNRVIISTGNALYLYFKSSLGEAGKGFSLRYIQGCKATITA 445
                       |.|.:.:|        |..|..|.                     ..|.|.:..
 Worm   287 -----------STTASPVT--------VAPSPANP---------------------SNCNAGLLM 311

  Fly   446 RNGTVTSPAFGLADYPK----NQECYFTIRNNARAPLSLKFDKFTVHKSDNVQVFDGSSTSGLRL 506
            ..|.:|||     :||:    |:.|.:.:.......::|:|..|:...:|.|.|:||.:|....|
 Worm   312 SPGVITSP-----NYPENYFNNENCTYQLSTLGAYKIALRFASFSTEANDVVTVYDGLTTDSPCL 371

  Fly   507 HSGNGFTGPAAPKLTLTASSGEMLIKFTSDALHNAAGWSATFSA 550
            ...:|...|.|    ||:|...||:.||||:...::|:.|.||:
 Worm   372 RRCSGTQRPFA----LTSSGNTMLVTFTSDSKGISSGFYARFSS 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
uif	NP_001162899.1	CLECT	36..167	CDD:214480	36/135 (27%)
		LDLa	172..206	CDD:238060	6/37 (16%)
		CUB	220..319	CDD:238001	18/111 (16%)
		CUB	326..435	CDD:238001	11/108 (10%)
		CUB	439..550	CDD:238001	35/114 (31%)
		PHA02927	<568..733	CDD:222943
		CCP	675..731	CDD:153056
		PHA02639	697..>834	CDD:165022
		FA58C	833..976	CDD:330301
		FXa_inhibition	988..>1016	CDD:464251
		CCP	1051..1106	CDD:153056
		FA58C	1303..1443	CDD:330301
		HYR	1463..1547	CDD:460572
		HYR	1548..1631	CDD:460572
		Ephrin_rec_like	1862..1909	CDD:429604
		Ephrin_rec_like	1916..1966	CDD:429604
		Ephrin_rec_like	1973..2020	CDD:429604
		EGF	2025..2055	CDD:394967
		EGF_CA	2059..2095	CDD:238011
		EGF_CA	2138..2176	CDD:238011
		EGF_CA	2178..2214	CDD:238011
		EGF_CA	2253..2289	CDD:238011
		EGF_CA	2292..2327	CDD:238011
		EGF_CA	2369..2405	CDD:238011
		EGF_CA	2411..2444	CDD:238011
		EGF_CA	2486..2520	CDD:238011
		EGF_CA	2522..2557	CDD:238011
		LamG	2590..2735	CDD:473984
		HYR	2799..2877	CDD:460572
		Ephrin_rec_like	3149..3200	CDD:429604
		Ephrin_rec_like	3207..3254	CDD:429604
		Ephrin_rec_like	3268..3307	CDD:429604
		Ephrin_rec_like	3315..3362	CDD:429604
clec-17	NP_493152.1	CLECT	24..152	CDD:214480	36/136 (26%)
		CLECT	165..280	CDD:214480	28/171 (16%)
		CUB	310..411	CDD:238001	33/109 (30%)