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Protein Alignment uif and crb1

DIOPT Version :9

Sequence 1:	NP_001162899.1	Gene:	uif / 33983	FlyBaseID:	FBgn0031879	Length:	3589	Species:	Drosophila melanogaster
Sequence 2:	XP_031756889.1	Gene:	crb1 / 100493588	XenbaseID:	XB-GENE-483760	Length:	1392	Species:	Xenopus tropicalis

Alignment Length:	1565	Identity:	374/1565 - (23%)
Similarity:	552/1565 - (35%)	Gaps:	431/1565 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  2094 CQEEASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCDVTIDPCTANGNPCGNGASCQALE 2158
            |.:..:.|.:..|.....|.:.                :.|..|.|||.:  |||...|.||.:.
Frog    27 CVDIEAQCSSPQCNGNLSCSST----------------EDCIGTKDPCLS--NPCSRNAKCQVIS 73

  Fly  2159 --QGRYKCECVPGWEGIHCEQNINDCSENPCLLGANCTDLVNDFQCACPPGFTGKRCEQKIDLCL 2221
              ...|.|:|..|:.|..|:.::..||.|||..|..|...::.|.|.|..|:.||.||...|.||
Frog    74 FVTQTYVCQCPVGFTGEKCDIHLKRCSRNPCGNGGECYVGIDGFICTCTAGYKGKLCETPEDECL 138

  Fly  2222 SEPCKHG-TCVDRLFDHECVCHPGWTGSACDINIDDCENRPCANEGTCVDLVDGYSCNCEPGYTG 2285
            ..||::| .|.:|..::.|.|.||:.|..|||.:|:|.::||.:...|::.:..|:|.|.|.|||
Frog   139 WNPCQNGAVCRNRRDEYACYCVPGFQGPLCDIEVDECISQPCHHGAICLNQIGKYTCMCPPQYTG 203

  Fly  2286 KNCQHTIDDCASNPCQHGATCVDQLDGFSCKCRPGYVGLSCEAEIDECLSDPCNPVGTERCLDLD 2350
            ::|:...|:|||.||.:||||.|.:..|:|.|.||:.|..|:..||||.|.||...|.  |:|.|
Frog   204 RDCELEADECASQPCLNGATCHDFIGSFNCTCPPGFEGDLCQFNIDECASYPCLNGGL--CIDGD 266

  Fly  2351 NKFECVCR-DGFKGPLCATDIDDCEAQPCLNNGICRDRVGGFECGCEPGWSGMRCEQQVTTCGAQ 2414
            |.:.|.|. .||.|..|...:..||.:||.||..|.:....|.|.|.||::|..||..::.|.:|
Frog   267 NGYTCECNMVGFIGMHCEMPVSMCEYKPCHNNATCLEGSAKFTCLCLPGYTGSLCEMDISECSSQ 331

  Fly  2415 APCQNDASCIDLFQ----------DYFCVCPSGTDGKNCETAPERCIGDPCMHGGKCQDFGSGLN 2469
             |||.|:.|::|.:          .|.|.|..|..|.:|||....|...||.:||.|::...|..
Frog   332 -PCQFDSECVELARPAMGTYNEHAGYICKCRKGLTGVHCETDINECESKPCQNGGTCENLHGGYT 395

  Fly  2470 CSCP--AD-----YSGIGCQYEYDACEEHVCQNGATCV----DNGAGYSCQCPPGFTGRNCEQDI 2523
            |.|.  ||     |.|..|:.....|..|.|.||.||:    :....:.|.||.|:.|.:|:
Frog   396 CHCKTHADVAGKYYGGRDCKELLFGCASHRCHNGGTCIPQLKEGEHSHYCLCPEGYAGPSCQ--- 457

  Fly  2524 VDCKDNSCPPGATCVDLTNGFYCQCPFNMTGDDC------RKAIQVDYDLYFSDPSRSTAAQVVP 2582
                                  .|..|:..|...      |...:.|:....|...::.....|.
Frog   458 ----------------------AQTTFSFNGKSVLPIHRNRSQTRGDHLFNISLSFQTVQTSAVI 500

  Fly  2583 FPTGEANSLTVAMWVQFAQKDDRGIFFTLYGVQSARMTQQRRMLLQAHSSGVQVSLFEDQPDAFL 2647
            |..|..|:                         |.|:..|...:..|.....|::.....|.
Frog   501 FHMGAQNT-------------------------SVRLYLQNSYIHLASEVNCQINSLLHLPH--- 537

  Fly  2648 SFGEYTSVNDGQWHHVAV------------------------------VWDGISGQLQLITEGLI 2682
                  :|:|.:||.|||                              :.|.:..|:.|..|..:
Frog   538 ------NVSDDRWHAVAVTLTDVLTLTLLDAQCNIRCTVNSDHIISTHLRDSVFQQMLLGGEPAV 596

  Fly  2683 --ASKMEYGAGGSLPGYLWAVLGLPQPYGLSNELAYSDSGFQGTITKAQVWARALDITSEIQKQV 2745
              |::....|..:.....|.| |..:.:.:       ||.|   :|...|....:|:..:.:.|
Frog   597 RTAAENNNDANNAEEMQAWFV-GCLRDFRI-------DSAF---VTDESVTVGDIDVGCKRRNQ- 649

  Fly  2746 RDCRSEPVLYPGLILN-WAGYEVTSGGVERNVPSLCGQRKCPVGYTGANCQQLVVDKEPPVVEHC 2809
              |..:|....|..:| |.||.             |   .|...|.|.||..          |:.
Frog   650 --CERQPCQNRGRCINLWLGYR-------------C---DCFRPYRGRNCSS----------EYE 686

  Fly  2810 PGDLWVIAKNGSAVVSWDEPHFSDNIGVTKIYERNGHRSGTTLLWG--TYDITYIASDAA----- 2867
            .|......:...|....|... |:.|.::..: |..||||..|..|  |...:.|:.|..
Frog   687 SGRFGQRQQTSYAAFQVDIDQ-SEEITISAFF-RTRHRSGILLSLGNSTNYHSVISLDGGIVTMK 749

  Fly  2868 ---------------GNTASCSFK---------VSL---------LTDFCPALADPVGG----SQ 2895
                           ||....|.|         |||         ||.........|||    .:
Frog   750 TISNVLLKANYTINNGNFHLVSLKLAQTKMEMFVSLKSVGQIDMGLTRVHSTSVLYVGGLADEKE 814

  Fly  2896 VCKDWGAGGQFKVCEIACNAGLRFSEPVPEFYT------------------CGAEGFWRPTREPS 2942
            ..|.   ||.|    :.|...||.:|...||:.                  |.::....|:...:
Frog   815 TTKH---GGYF----MGCVQDLRIAETHLEFFPSSESSTVGNITVSNVTQGCKSDSECNPSTCHN 872

  Fly  2943 MPLVYP-------SCSPSKPAQRVFRIKMLFPSDVLCNKAGQAVLRQKVTNSVNGLNRDWNFCSY 3000
            ..:.||       ||.|:                 ...||.:.::..::|....|     :.|..
Frog   873 GGICYPVWDDFVCSCPPN-----------------TTGKACEDLMWCQLTQCPPG-----SVCQT 915

  Fly  3001 AIEGTRECKDIQIDVKCDH---YRGTQNNRVRRQAKDGGV----YVMEAELPVVNDDDDDLTLTG 3058
            ...| .||....:.....|   ||  .|.::.|...:..:    ...|:.|.....:.|.||:..
Frog   916 VPSG-YECTTSVVFNGTSHGVMYR--SNGKIARDLTNVTLQFRTQASESILLYAEQEPDILTIAI 977

  Fly  3059 RQGRQQTGGDTYTLEIAFPAANDPVVHTSTGERSTVKQLLEKLILEDDQFAVQEILPNTVPDPAS 3123
            ::.|.                   :.|..:|.......|....::.|:|:. ...|..|.|:..|
Frog   978 QRSRL-------------------LFHLQSGNSLDAVSLYGAELVNDNQWH-NITLSMTTPESHS 1022

  Fly  3124 ----------LELGSEYACPVGQVVMIPDCVPCAIGTFYDSANKTCIAC-----SRGTYQSEAG- 3172
                      :::.|.:  |.|.:..:.:.....:|......|...:.|     ..|.|.|..|
Frog  1023 SHWQMALDGKMDIISLF--PTGNLNFLREGTDIYLGINGKDGNLHFLGCLGMVQIGGIYLSYFGD 1085

  Fly  3173 -QLQCSKCPVIAGRP---------GVTAGPGARSAADC-KERCPAGKYFDAETGLCRSCGHGFYQ 3226
             ..|.:       ||         .|:.|....|:..| .:.|..|.          :|..||..
Frog  1086 DDYQVT-------RPQKEQFIRVSAVSVGIDCLSSESCVSQHCMHGD----------NCRGGFTH 1133

  Fly  3227 PNEGSFSCELCGLGQTTRSTEATSRKECRDECSSGQQLGADGRCEPCPRG--TYRLQGVQPSCAA 3289
            |     .| .|..|:|....|..:.|     |.|          .||..|  |..:.|....|
Frog  1134 P-----IC-TCPPGRTGAFCETYTNK-----CHS----------SPCLHGNCTDTITGYLCKC-- 1175

  Fly  3290 CPLGRTTPKVGASSVEECTLPVCSAGTYLNATQNMCIECRKGYYQSESQQTSCLQCPPNHSTKIT 3354
                    :||.|.: .|.:..|.  .:..||...||....||        ||| ||.|.:..:.
Frog  1176 --------QVGYSGI-NCDIHNCQ--DHQCATGATCIGQAYGY--------SCL-CPANVTGVLC 1220

  Fly  3355 GATSKSECTN----------PCEHIAEGKPH--CDVNAYCIMVPETSDFKCECKPGFNGTGMAC- 3406
            ..:|.||.::          |......||.:  |...:.|  ..|..:..|.|.|||  .|..|
Frog  1221 SVSSPSEASSLNLVRIYNRLPSTICGNGKKNITCYNRSNC--TEERGELGCACLPGF--VGERCE 1281

  Fly  3407 --TDVCDGF-CENSGACVKDLKGTPSCRCVGSFTGPHC-AERSEFAYIAGGIAGAVIFIIIIVLL 3467
              .|.|:.. |.|.|.| ::|.....|.|..:|.|.|| .:.|:|  :..|:..||..:::  .|
Frog  1282 IDVDECESNPCLNGGLC-QNLPNRFHCICDLNFAGEHCEIDLSDF--LPPGVFTAVASVVL--AL 1341

  Fly  3468 IWMIC 3472
            .:::|
Frog  1342 FFIVC 1346

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.