Protein Alignment uif and dner

DIOPT Version :10

• Sequence 1: NP_001162899.1
• Gene: uif / 33983
• FlyBaseID: FBgn0031879
• Length: 3589
• Species: Drosophila melanogaster
• Sequence 2: NP_001269415.2
• Gene: dner / 100332110
• ZFINID: ZDB-GENE-130502-1
• Length: 745
• Species: Danio rerio
• Alignment Length: 673
• Identity: 193/673 - (28%)
• Similarity: 261/673 - (38%)
• Gaps: 184/673 - (27%)

  Fly  2009 TDSPASKGREQCKPVVCGEGACQHGGLCVPMG--HDIQ-------------CFCPAGFSGRRCEQ 2058
            |.||.........|..|....|.:||:|..:|  .|.|             |.|..||:|:.||.
Zfish    25 TSSPGPGEDPSTAPDPCEGRPCLNGGVCSRLGEMEDSQSTQMQTLEPWAYICVCSRGFTGQNCEF 89

  Fly  2059 DIDECASQPCYNGGQCKD-LPQGYRCECPAGYSGINC---------QEEASDCGNDTCPARAMCK 2113
            ..|.|||.||.:|...:| ..:|:.|||..||||..|         .|...|......|..|...
Zfish    90 FADPCASSPCLHGNCSQDGEGEGFSCECSEGYSGARCDLPTLTFDLSESTWDLAESLVPEHATPA 154

  Fly  2114 NEPGYKNVTCLCR--SGYTGDQCDVTIDP------------------------CTAN-------- 2144
            ........|.:.:  :..|..|...|::|                        |.:.
Zfish   155 TPATPATTTQVLQPTTVLTTTQAPPTLEPWQPRAGQRVLEILWDDQQITNEAECVSTAGGESAGM 219

  Fly  2145 ----------------GNPCGNGASCQALEQGRYKCECVPG---W-----EG------------- 2172
                            ||..|:....:....|..:|....|   |     ||
Zfish   220 MSISLELAEETAVKLVGNVSGSAVLWRVGASGYEQCSVADGTIMWFQQSSEGLVLPDQSLPLGHN 284

  Fly  2173 -------------------IHCEQNINDCSENPCLLGANCTDLVNDFQCACPPG--FTGKRCEQK 2216
                               :|.....|:|.|                     ||  |:..:|..|
Zfish   285 YFISVLHVGSPSGPEVTLRLHLLVKTNNCME---------------------PGSAFSDPQCSGK 328

  Fly  2217 IDLCLSEPCKHGTCVDRLFDHECVCHPGWTGSACDINIDDCENRPCANEGTCVDL-----VDGYS 2276
             ..|:::     :.||..:   |.|..|::|..|: ..|.|..:||.|.|:|.||     ...|:
Zfish   329 -GKCVTQ-----SSVDTFY---CRCDDGYSGIFCE-EFDACHLKPCENNGSCADLRQRDEGQNYT 383

  Fly  2277 CNCEPGYTGKNCQHTIDDCASNPCQHGATCVDQLDGFSCKCRPGYVGLSCEAEIDECLSDP---- 2337
            |.|:.|:.|:.||..:|.|.|.||::||||...|:|..|.|..||.|:.||.:||.|.|.|
Zfish   384 CTCQTGFEGERCQSLVDHCVSGPCRNGATCSSSLEGPHCYCAEGYQGIMCEQKIDPCASGPCHNN 448

  Fly  2338 --CNPVGTERCLDLDNKFECVCRDGFKGPLCATDIDDCEAQPCLNNGICRDRVGGFECGCEPGWS 2400
              |:|.|.      ...|.|.|..||.||.||..:|.|...||. :||||.....:.|.|.||:.
Zfish   449 ASCSPQGA------GLGFSCTCPAGFTGPTCAQLVDFCALNPCA-HGICRSIGTSYRCLCVPGYH 506

  Fly  2401 GMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAPERCIGDPCMHGGKCQDFG 2465
            |:.||::...| ..|||||.|:|.||...|.|:|.|...||:||...:.|:...|.:||.|:..|
Zfish   507 GLYCEEEYNEC-LSAPCQNYATCRDLINAYECICASQFTGKHCEIYKDPCLKLRCQNGGHCESGG 570

  Fly  2466 SGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDI------- 2523
            ...:|.||..|.|..|:.:.:.||.:.|.:|.||:|...||:|.||||:.|.:||..:
Zfish   571 RNASCVCPPGYMGENCEVDVNECESNPCHHGGTCIDQSNGYTCHCPPGWVGGSCEIHLQWKMAQP 635

  Fly  2524 VDCKDNSCPP--------GATCV 2538
            ||...|.  |        ||.||
Zfish   636 VDSLTNM--PRHSLYIIIGALCV 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
uif	NP_001162899.1	CLECT	36..167	CDD:214480
		LDLa	172..206	CDD:238060
		CUB	220..319	CDD:238001
		CUB	326..435	CDD:238001
		CUB	439..550	CDD:238001
		PHA02927	<568..733	CDD:222943
		CCP	675..731	CDD:153056
		PHA02639	697..>834	CDD:165022
		FA58C	833..976	CDD:330301
		FXa_inhibition	988..>1016	CDD:464251
		CCP	1051..1106	CDD:153056
		FA58C	1303..1443	CDD:330301
		HYR	1463..1547	CDD:460572
		HYR	1548..1631	CDD:460572
		Ephrin_rec_like	1862..1909	CDD:429604
		Ephrin_rec_like	1916..1966	CDD:429604
		Ephrin_rec_like	1973..2020	CDD:429604	3/10 (30%)
		EGF	2025..2055	CDD:394967	13/44 (30%)
		EGF_CA	2059..2095	CDD:238011	17/45 (38%)
		EGF_CA	2138..2176	CDD:238011	12/125 (10%)
		EGF_CA	2178..2214	CDD:238011	6/37 (16%)
		EGF_CA	2253..2289	CDD:238011	14/40 (35%)
		EGF_CA	2292..2327	CDD:238011	16/34 (47%)
		EGF_CA	2369..2405	CDD:238011	13/35 (37%)
		EGF_CA	2411..2444	CDD:238011	16/32 (50%)
		EGF_CA	2486..2520	CDD:238011	15/33 (45%)
		EGF_CA	2522..2557	CDD:238011	8/32 (25%)
		LamG	2590..2735	CDD:473984
		HYR	2799..2877	CDD:460572
		Ephrin_rec_like	3149..3200	CDD:429604
		Ephrin_rec_like	3207..3254	CDD:429604
		Ephrin_rec_like	3268..3307	CDD:429604
		Ephrin_rec_like	3315..3362	CDD:429604
dner	NP_001269415.2	None