Protein Alignment CCDC39 and ccdc39

DIOPT Version :10

• Sequence 1: NP_852091.1
• Gene: CCDC39 / 339829
• HGNCID: 25244
• Length: 941
• Species: Homo sapiens
• Sequence 2: NP_001410743.2
• Gene: ccdc39 / 100005620
• ZFINID: ZDB-GENE-110603-1
• Length: 947
• Species: Danio rerio
• Alignment Length: 948
• Identity: 477/948 - (50%)
• Similarity: 679/948 - (71%)
• Gaps: 14/948 - (1%)

Human     1 MSSEFLAELHWEDGFAIPVANEENKLLEDQLSKLKDERASLQDELREYEERINSMTSHFKNVKQE 65
            |||..|.|:.|:..|||||||.|||.||:|:.|.:.:..:|.::|.::::.||::|.|.||:|||
Zfish     1 MSSALLEEVGWDADFAIPVANAENKALEEQIRKKQKDILNLDNKLNKHKDVINALTEHLKNLKQE 65

Human    66 LSITQSLCKARERETESEEHFKAIAQRELGRVKDEIQRLENEMASILEKKSDKENGIFKATQKLD 130
            :|..|:||||:|:|||||.|.||:|:||.||:|.||.|||:::.::.|||:.:||.|||||||:|
Zfish    66 VSHNQALCKAKEKETESEVHLKALAERETGRLKQEITRLESQLTTLNEKKNAQENSIFKATQKID 130

Human   131 GLKCQMNWDQQALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLERLTLECNQKRKILDNE 195
            .|..|:|||||.|||:|:||||||.|.:.:.|||:||:.||:.|||.:|:||||.|||||.||||
Zfish   131 ELTSQLNWDQQTLEAFLQESAHKDEDTMAIIKYAKQDERKIKELTLNIEKLTLESNQKRKTLDNE 195

Human   196 LTETISAQLELDKAAQDFRKIHNERQELIKQWENTIEQMQKRDGDIDNCALELARIKQETREKEN 260
            ||||:::|:.|||.|:.||:.|.||||||.|||||||||:|||.||..||:.||.:.|..|||.:
Zfish   196 LTETVTSQIALDKTAESFRQAHTERQELISQWENTIEQMRKRDQDIQQCAMMLAELNQTIREKND 260

Human   261 LVKEKIKFLESEIGNNTEFEKRISVADRKLLKCRTAYQDHETSRIQLKGELDSLKATVNRTSSDL 325
            |:||:..|||.||.||.|.|:.|...:|:..:.|...|:.|.::.:|:.|::.||.||:||::|:
Zfish   261 LIKERKDFLEREIENNKELERNIGTVERQAFRLRQQLQEEEKNQRRLQDEVEVLKGTVDRTATDV 325

Human   326 EALRKNISKIKKDIHEETARLQKTKNHNEIIQTKLKEITEKTMSVEEKATNLEDMLKEEEKDVKE 390
            |..|..:|.:||||.::|.::::.:.||..::.||:.:||..::.||:|..:|.:|:|:|:::||
Zfish   326 ETSRSQLSSMKKDIQDKTTKVEEAQLHNAALEEKLRMVTEAVLNGEEQAAQMEQLLREQEQNIKE 390

Human   391 VDVQLNLIKGVLFKKAQELQTETMKEKAVLSEIEGTRSSLKHLNHQLQKLDFETLKQQEIMYSQD 455
            :|.||...|.:||||:||:|....|||.|.:||..||::|.:|:.:|:|||...|:||.|:.:||
Zfish   391 IDSQLLRQKELLFKKSQEVQALRDKEKNVTAEICATRTALSNLDSKLRKLDQNFLQQQMIISNQD 455

Human   456 FHIQQVERRMSRLKGEINSEEKQALEAKIVELRKSLEEKKSTCGLLETQIKKLHNDLYFIKKAHS 520
            |.||.:||:...|:|::|:|||:|||.|:.:|..||||||.|...|..|:|||.:|:..|||...
Zfish   456 FQIQMLERKTLHLQGKVNTEEKKALEKKVADLAASLEEKKKTAANLNKQLKKLQDDIRCIKKDTE 520

Human   521 KNSDEKQSLMTKINELNLFIDRSEKELDKAKGFKQDLMIEDNLLKLEVKRTREMLHSKAEEVLSL 585
            |...||.:|.|||.|:.|||:.||||..|::..|||.|:|..|||:||:|.|.:|:.:|:.||:|
Zfish   521 KIGAEKTNLSTKIQEVELFIETSEKERKKSRLKKQDSMVEKGLLKMEVQRLRNLLYDRADGVLTL 585

Human   586 EKRKQQLYTAMEERTEEIKVHKTMLASQIRYVDQERENISTEFRERLSKIEKLKNRYEILTVVML 650
            |||:.||.|||:||.|||:||:.||..|::..:|||:.:|....|.:|||:|.:.|||:|:|.:.
Zfish   586 EKRRLQLQTAMKEREEEIRVHREMLNKQVKLTEQERQGLSAAVNEAMSKIDKQRKRYEVLSVSLA 650

Human   651 PPEGEEEKTQAYYVIKAAQEKEELQREGDCLDAKINKAEKEIYALENTLQVLNSCNNNYKQSFKK 715
            ||||||:|:|||::||||||||||||:||.|||||.|.||||:||||||||:|:||:.::::..|
Zfish   651 PPEGEEDKSQAYFIIKAAQEKEELQRKGDELDAKIRKTEKEIHALENTLQVVNNCNSTHRKALTK 715

Human   716 VTPSSDEYELKIQLEEQKRAVDEKYRYKQRQIRELQEDIQSMENTLDVIEHLANNVKEKLSEKQA 780
            ||.||..::.|::||||:||.:|||:||:||.:||||||:||.|||:.:......:.|.:...||
Zfish   716 VTESSPAHQEKLKLEEQRRAAEEKYKYKRRQTQELQEDIESMSNTLEGLLQEEKVLNEGIERTQA 780

Human   781 YSFQLSKETEEQKPKLERVTKQCAKLTKEIRLLKDTKDETMEEQDIKLREMKQFHKVIDEMLVDI 845
            :...|:|:...|:.|:.|..|||||.|||||..|.:.::|.||:||:|||::.|:|.|::||:|.
Zfish   781 HVLSLNKDILSQEEKINRAVKQCAKYTKEIRSGKQSTEKTFEERDIELRELRDFNKSINKMLLDA 845

Human   846 IEENTEIRIILQTYFQQSGLELPTASTKGSRQSSRSPSHTSLSARSSRSTSTSTSQS-------- 902
            :|.|.|:..|||.:|.|:||.||:.|:..|.:.|..||....||...||::.|.|.|
Zfish   846 MEGNPELSSILQIHFTQAGLSLPSPSSTPSSRLSSKPSSARSSASLHRSSNLSASSSPRSQSVSS 910

Human   903 -SIKVLELKFPASSSLVGSP--SRPSSASSSSSNVKSK 937
             .:|.::|....|   |.||  |:||||.||.|:.|.|
Zfish   911 PQMKTVDLGLGLS---VTSPRGSQPSSAGSSRSSSKCK 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCDC39	NP_852091.1	SMC_prok_B	26..862	CDD:274008	428/835 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	868..941		29/81 (36%)
ccdc39	NP_001410743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	866..947		30/83 (36%)