Protein Alignment snRNP-U1-70K and TRA2B

DIOPT Version :10

• Sequence 1: NP_477205.1
• Gene: snRNP-U1-70K / 33982
• FlyBaseID: FBgn0016978
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_004584.1
• Gene: TRA2B / 6434
• HGNCID: 10781
• Length: 288
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 66/243 - (27%)
• Similarity: 103/243 - (42%)
• Gaps: 42/243 - (17%)

  Fly    63 QERLERRRREKAEQVAYKLEREIALWDPTEIK------NATEDPFRTLFIARINYDTSESKLRRE 121
            :.|..||.|.::....|: .|......|...:      .|..||...|.:..::..|:|..||..
Human    74 RSRSHRRSRSRSYSRDYR-RRHSHSHSPMSTRRRHVGNRANPDPNCCLGVFGLSLYTTERDLREV 137

  Fly   122 FEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGW 186
            |..||||..:.:::||:|.:.:|:||:.:|:..|...|.:.|:|.::|.:|:.||....:.
Human   138 FSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKR---- 198

  Fly   187 LPRRLGGGL-------GGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLD 244
             |.....|:       |.:||           |:..:|..:|...:|:...|...|.|||
Human   199 -PHTPTPGIYMGRPTYGSSRR-----------RDYYDRGYDRGYDDRDYYSRSYRGGGGG----- 246

  Fly   245 ARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRR 292
               |.|:.|.:.|.:...||.......||..    |||||||....||
Human   247 ---GGGWRAAQDRDQIYRRRSPSPYYSRGGY----RSRSRSRSYSPRR 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_477205.1	U1snRNP70_N	3..92	CDD:432406	7/28 (25%)
		RRM_snRNP70	101..188	CDD:409682	25/86 (29%)
TRA2B	NP_004584.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		8/40 (20%)
		RRM_TRA2	117..196	CDD:409798	25/78 (32%)
		Linker	193..230		8/52 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..225		6/44 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..288		21/58 (36%)