DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snRNP-U1-70K and Rox8

DIOPT Version :9

Sequence 1:	NP_001260173.1	Gene:	snRNP-U1-70K / 33982	FlyBaseID:	FBgn0016978	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	149	Identity:	40/149 - (26%)
Similarity:	62/149 - (41%)	Gaps:	22/149 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 LEREIAL-W--DPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKP 142
            ||:||.: |  .|.............:|:..::.:.....||..|..:|.|....::.|..:.|.
  Fly    71 LEKEIKVNWATSPGNQPKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKS 135

  Fly   143 KGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRL--------GGGLGGTR 199
            |||||:.:..:.:...|.:..:|:.|.|:.:       ||  .|..|:|        |||.||..
  Fly   136 KGYAFVSFVKKAEAENAIQAMNGQWIGSRSI-------RT--NWSTRKLPPPREPSKGGGQGGGM 191

  Fly   200 RG--GNDVNIKHSGREDNE 216
            .|  ||...:|.|.|...|
  Fly   192 GGGPGNGSGVKGSQRHTFE 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_001260173.1	U1snRNP70_N	2..92	CDD:289024	6/13 (46%)
		RRM	<97..>179	CDD:223796	17/81 (21%)
		RRM_snRNP70	101..188	CDD:240682	20/86 (23%)
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	40/149 (27%)
		RRM1_TIA1_like	9..80	CDD:240798	4/8 (50%)
		RRM2_TIA1_like	96..170	CDD:240799	19/82 (23%)
		RRM3_TIA1_like	221..294	CDD:240800
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910