DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snRNP-U1-70K and Snrnp35

DIOPT Version :9

Sequence 1:	NP_001260173.1	Gene:	snRNP-U1-70K / 33982	FlyBaseID:	FBgn0016978	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001014149.1	Gene:	Snrnp35 / 360803	RGDID:	1310724	Length:	244	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	95/265 - (35%)
Similarity:	129/265 - (48%)	Gaps:	71/265 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 KNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHA 158
            |..|.||..|||:||:|..|.|.||:..|..||.|:::.|:.|..:|..||||||||:.||.:..
  Rat    43 KGVTGDPLLTLFVARLNSQTKEEKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERALLK 107

  Fly   159 AYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYR 223
            ||:.|||..||...:.||.|..||::||:||||||||||.:..|   .::..||:...|:.....
  Rat   108 AYRDADGLVIDQHEIFVDYELERTLRGWIPRRLGGGLGGKKESG---QLRFGGRDRPFRKPINLP 169

  Fly   224 LEREREDREGPGRGGGSNGLDARPGRGFGAERR-RSRSRER----RDRERDRGRGAVASNGRSRS 283
            :.:....|||.                  .||| |||||:|    |.||||..||
  Rat   170 VVKNEPHREGK------------------RERRERSRSRDRHWDPRPRERDHDRG---------- 206

  Fly   284 RSRERRKRRAGSRERYDEFDRRDRRDRER---ERDRDREREKKKKRSKSRERESSRERRERKRER 345
                        ||::       .:||.|   |.|.:||||.:.:|:|:             |::
  Rat   207 ------------REKH-------WQDRARVWPENDWEREREFRDERAKT-------------RDK 239

  Fly   346 RDRER 350
            |||.:
  Rat   240 RDRSK 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_001260173.1	U1snRNP70_N	2..92	CDD:289024
		RRM	<97..>179	CDD:223796	39/81 (48%)
		RRM_snRNP70	101..188	CDD:240682	41/86 (48%)
Snrnp35	NP_001014149.1	RRM	<41..>126	CDD:223796	39/82 (48%)
		RRM_snRNP35	48..137	CDD:240683	43/88 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	146..244		41/160 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto97012
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910