Protein Alignment snRNP-U1-70K and Ncl

DIOPT Version :10

• Sequence 1: NP_477205.1
• Gene: snRNP-U1-70K / 33982
• FlyBaseID: FBgn0016978
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_036881.2
• Gene: Ncl / 25135
• RGDID: 3153
• Length: 714
• Species: Rattus norvegicus
• Alignment Length: 260
• Identity: 73/260 - (28%)
• Similarity: 101/260 - (38%)
• Gaps: 84/260 - (32%)

  Fly    25 VDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWD 89
            |.:.|| .||:||..:.  .|.|||.|            |.|....:.:.|....:||    |..
  Rat   518 VPQNPH-GKSKGYAFIE--FASFEDAK------------EALNSCNKMEIEGRTIRLE----LQG 563

  Fly    90 PTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHER 154
            |....||...|.:|||:..::.||:|..|:..||  |.::..: :.|:|:|..||:.|:::..|.
  Rat   564 PRGSPNARSQPSKTLFVKGLSEDTTEETLKESFE--GSVRARI-VTDRETGSSKGFGFVDFNSEE 625

  Fly   155 DMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERER 219
            |..||.:..:..:||..:|.:|         |...:..||.||  |||.
  Rat   626 DAKAAKEAMEDGEIDGNKVTLD---------WAKPKGEGGFGG--RGGG---------------- 663

  Fly   220 ERYRLEREREDREG-PGRGGGSNGLDARPGR-GFGAERRRSRSRERRDRERDRGRGAVASNGRSR 282
                       |.| .|||||      |.|| |||.                ||||.....|..|
  Rat   664 -----------RGGFGGRGGG------RGGRGGFGG----------------RGRGGFGGRGGFR 695

  Fly   283  282
              Rat   696  695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_477205.1	U1snRNP70_N	3..92	CDD:432406	19/66 (29%)
		RRM_snRNP70	101..188	CDD:409682	25/86 (29%)
Ncl	NP_036881.2	8 X 8 AA tandem repeats of X-T-P-X-K-K-X-X	58..135
		RRM1_NCL	312..386	CDD:409837
		RRM2_NCL	395..470	CDD:409838
		RRM3_NCL	489..561	CDD:409839	17/61 (28%)
		RRM4_NCL	576..653	CDD:409840	25/88 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	646..714		28/110 (25%)