Protein Alignment snRNP-U1-70K and tiar-2

DIOPT Version :10

• Sequence 1: NP_477205.1
• Gene: snRNP-U1-70K / 33982
• FlyBaseID: FBgn0016978
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_496718.1
• Gene: tiar-2 / 174909
• WormBaseID: WBGene00012904
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 269
• Identity: 62/269 - (23%)
• Similarity: 87/269 - (32%)
• Gaps: 85/269 - (31%)

  Fly    46 DFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTE--IKNATEDPFRTLFIAR 108
            :|.|.....|.......:|.|     ||...|.:..|..    :|.|  .|..|...|. :|:..
 Worm    84 EFSDHNQATLALQSHNGRELL-----EKEMHVTWAFEPR----EPGENRSKPETSRHFH-VFVGD 138

  Fly   109 INYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRV 173
            :..:...:|||..|..:|.:.:..:|.|..:.|.|||.|:.|....|...|....:|
 Worm   139 LCSEIDSTKLREAFVKFGEVSEAKIIRDNNTNKGKGYGFVSYPRREDAERAIDEMNG-------- 195

  Fly   174 LVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGG 238
                       .||.||.......||:..          ||.||                    |
 Worm   196 -----------AWLGRRTIRTNWATRKPD----------EDGER--------------------G 219

  Fly   239 GSNGLDARPGRGFGAERRRSRSRERRDRERDRGR--------GAVASNGRSRSRSRERRKRRAGS 295
            |..| |.|.|.|.|.:|..::|.:..|...::..        |.:|:.|       |...|||
 Worm   220 GDRG-DRRGGGGGGRDRYHNQSEKTYDEIFNQAAADNTSVYVGNIANLG-------EDEIRRA-- 274

  Fly   296 RERYDEFDR 304
                  |||
 Worm   275 ------FDR 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_477205.1	U1snRNP70_N	3..92	CDD:432406	10/45 (22%)
		RRM_snRNP70	101..188	CDD:409682	19/86 (22%)
tiar-2	NP_496718.1	PABP-1234	41..>317	CDD:130689	62/269 (23%)
		RRM_SF	133..207	CDD:473069	21/93 (23%)
		RRM3_TIA1_like	256..325	CDD:409790	10/37 (27%)