DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snRNP-U1-70K and rsp-5

DIOPT Version :9

Sequence 1:	NP_001260173.1	Gene:	snRNP-U1-70K / 33982	FlyBaseID:	FBgn0016978	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_495307.3	Gene:	rsp-5 / 174073	WormBaseID:	WBGene00004702	Length:	208	Species:	Caenorhabditis elegans

Alignment Length:	255	Identity:	75/255 - (29%)
Similarity:	104/255 - (40%)	Gaps:	72/255 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 LFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKI 168
            |::.:|.|:..|..:.|..:.||.|..|.:.:        |:||:::|..||...|....|||.:
Worm     4 LYLGKIPYNARERDVERFLKGYGKINNISMKY--------GFAFVDFEDSRDAEDACHDLDGKTM 60

  Fly   169 D--SKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDR 231
            :  |.|::|::.|.:      ||            |||   :|..|....|.|     ...|..|
Worm    61 EGSSMRLVVEMARGK------PR------------GND---RHGSRSPRRRSR-----SPRRRSR 99

  Fly   232 EGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSR 296
            ..|                    |||||||:|:...|.|.|    |:.||||..||.| ||:.||
Worm   100 TPP--------------------RRRSRSRDRKRSRRSRSR----SSSRSRSPVRESR-RRSESR 139

  Fly   297 ERYDEFDRRDRRDRERE----RDRDREREKK-------KKRSKSRERESSRERRERKRER 345
            ....:.|.:....|.|.    :||.|.|...       :|||.||.|..||:...|...|
Worm   140 SPSPKRDLKREASRSRSPLPAKDRSRTRSGSPPKNGGDRKRSVSRGRSHSRDGSNRSVSR 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_001260173.1	U1snRNP70_N	2..92	CDD:289024
		RRM	<97..>179	CDD:223796	22/76 (29%)
		RRM_snRNP70	101..188	CDD:240682	23/85 (27%)
rsp-5	NP_495307.3	RRM	<3..>77	CDD:223796	23/86 (27%)
rsp-5	NP_495307.3	RRM_SF	3..74	CDD:302621	22/77 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910