DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snRNP-U1-70K and CSTF2

DIOPT Version :9

Sequence 1:	NP_001260173.1	Gene:	snRNP-U1-70K / 33982	FlyBaseID:	FBgn0016978	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001293135.1	Gene:	CSTF2 / 1478	HGNCID:	2484	Length:	597	Species:	Homo sapiens

Alignment Length:	106	Identity:	33/106 - (31%)
Similarity:	58/106 - (54%)	Gaps:	6/106 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 DPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHE 153
            ||     |.:...|::|:..|.|:.:|.:|:..|...||:....|::|:|:||||||.|.||:.:
Human     8 DP-----AVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQ 67

  Fly   154 RDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGG 194
            ....:|.::.:|::...:.:.||...:...|..| :.||.|
Human    68 ETALSAMRNLNGREFSGRALRVDNAASEKNKEEL-KSLGTG 107

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_001260173.1	U1snRNP70_N	2..92	CDD:289024	2/2 (100%)
		RRM	<97..>179	CDD:223796	25/81 (31%)
		RRM_snRNP70	101..188	CDD:240682	26/86 (30%)
CSTF2	NP_001293135.1	PABP-1234	4..352	CDD:130689	33/106 (31%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	24/73 (33%)
		CSTF2_hinge	112..191	CDD:373015
		PRK14718	<412..>469	CDD:173181
		CSTF_C	553..593	CDD:373006
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1455080at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920