Protein Alignment snRNP-U1-70K and SRSF12

DIOPT Version :10

• Sequence 1: NP_477205.1
• Gene: snRNP-U1-70K / 33982
• FlyBaseID: FBgn0016978
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_542781.3
• Gene: SRSF12 / 135295
• HGNCID: 21220
• Length: 261
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 74/282 - (26%)
• Similarity: 109/282 - (38%)
• Gaps: 77/282 - (27%)

  Fly    97 TEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYK 161
            |..|..:|||..:...|....|||||..||||..:.:..|..:.:|:|:|::::|..||...|..
Human     5 TRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALY 69

  Fly   162 HADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLER 226
            :.:.|                   |:                      .||:        ..::.
Human    70 NLNRK-------------------WV----------------------CGRQ--------IEIQF 85

  Fly   227 EREDREGPGRGGGSNGLDARPGRGFGAERRRSRS-RERRDRERDRGRGAVASNGRSRSR------ 284
            .:.||:.||:..........|     ::.||||| .:||.|.|.      :|.||:|.|
Human    86 AQGDRKTPGQMKSKERHPCSP-----SDHRRSRSPSQRRTRSRS------SSWGRNRRRSDSLKE 139

  Fly   285 SRERR------KRRAGSRERYDEFDRRDRRDRERERDRDREREKK-KKRSKS-RERESSRERRER 341
            ||.||      |.|:.|..|.....|:.|..|.....|.|.|.|. :||||| .:.:||..:::.
Human   140 SRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQT 204

  Fly   342 KRERRDRERGTGSGGDVKERKP 363
            ....:.|..|..|  |...|.|
Human   205 SSGTKSRSHGRHS--DSIARSP 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_477205.1	U1snRNP70_N	3..92	CDD:432406
		RRM_snRNP70	101..188	CDD:409682	23/86 (27%)
SRSF12	NP_542781.3	RRM_SRSF10_SRSF12	10..93	CDD:240758	27/131 (21%)
		PABP-1234	<12..211	CDD:130689	66/258 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..261		47/152 (31%)