DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment snRNP-U1-70K and srsf4

DIOPT Version :9

Sequence 1:	NP_001260173.1	Gene:	snRNP-U1-70K / 33982	FlyBaseID:	FBgn0016978	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	XP_004911639.2	Gene:	srsf4 / 100038227	XenbaseID:	XB-GENE-493077	Length:	741	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	85/286 - (29%)
Similarity:	127/286 - (44%)	Gaps:	58/286 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 LFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKI 168
            ::|.|:::...|..:.|.|:.:|.|.::.|        ..||.|:|:|..||...|....:|:::
Frog     9 VYIGRLSHRARERDVERFFKGFGKIVEVDL--------KNGYGFVEFEDSRDAEDAVYEMNGREL 65

  Fly   169 DSKRVLVDVERARTVKGWLPRR-LGGGLGGTRRGGNDVNIKHSGREDNERERERYRLERE----- 227
            ..:||:|:..||       ||| :..|. |.|:||:|        :.....|..|||..|
Frog    66 CGERVIVEHARA-------PRRDIRSGY-GYRKGGSD--------KYGPPVRTMYRLRVENLSSR 114

  Fly   228 ---REDREGPGRGGGSNGLDARPGR-GFGAERRRSRSRERR-------------------DRERD 269
               ::.::...:.|.....||...| ..|....||.|..||                   ||...
Frog   115 CSWQDLKDFMRQAGEVTYADAHQRRQNEGVIEFRSYSDMRRALEKLDGSEINGRKIQLVEDRAGS 179

  Fly   270 RGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRSKSRERES 334
            |.:|   |:.|||||||.||.|.:.||.|  ...|...|.|:|||.|.|.:|::..||.||:|..
Frog   180 RNKG---SSSRSRSRSRSRRSRSSHSRSR--SRSRSHSRSRQRERSRSRSKERRSSRSHSRKRRE 239

  Fly   335 SRERRERKRERRDRERGTGSGGDVKE 360
            ||...:|:|:.|...:|..:...|.:
Frog   240 SRSISKRRRQSRSVSKGRRASRSVSK 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-70K	NP_001260173.1	U1snRNP70_N	2..92	CDD:289024
		RRM	<97..>179	CDD:223796	20/74 (27%)
		RRM_snRNP70	101..188	CDD:240682	22/83 (27%)
srsf4	XP_004911639.2	RRM_SF	6..77	CDD:418427	20/75 (27%)
		RRM_SF	104..176	CDD:418427	14/71 (20%)
		ser_rich_anae_1	<249..>456	CDD:411418	3/17 (18%)
		PRK12678	352..>573	CDD:237171
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910