Protein Alignment Hmgcl and LYS21

DIOPT Version :10

• Sequence 1: NP_609089.1
• Gene: Hmgcl / 33978
• FlyBaseID: FBgn0031877
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_010151.1
• Gene: LYS21 / 851425
• SGDID: S000002289
• Length: 440
• Species: Saccharomyces cerevisiae
• Alignment Length: 276
• Identity: 60/276 - (21%)
• Similarity: 115/276 - (41%)
• Gaps: 56/276 - (20%)

  Fly    11 ALTAKRTAVT-------------SAANQVRIVEVGPRDGLQNEPKLLPAATKIELINQLSETGLR 62
            ::|...||.|             |.....::::...|:|.|..........|||:...|.:.|:.
Yeast     9 SVTESTTAPTTSNPYGPNPADYLSNVKNFQLIDSTLREGEQFANAFFDTEKKIEIARALDDFGVD 73

  Fly    63 TIEATSFVSAKW-------VPQMGDNAEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVF 120
            .||.||.|:::.       :.::|..|::|..||           .::.....|:|.|.:.|.|.
Yeast    74 YIELTSPVASEQSRKDCEAICKLGLKAKILTHIR-----------CHMDDARVAVETGVDGVDVV 127

  Fly   121 GAASDAFSL----KNVNCTAAEAIERFKPVLKAAQKHGVRVR-----GYVSTVVGCPYEGAVAPS 176
            ...|.....    |::|..|..|:|    |::..:..|:.:|     .:.|.:|.
Yeast   128 IGTSKFLRQYSHGKDMNYIAKSAVE----VIEFVKSKGIEIRFSSEDSFRSDLVD---------- 178

  Fly   177 AVVKVVEALYQMGCYEISLGDTIGVGTPGTMRRMLDEVTKVVPAKDLAVHCHDTYGQALSNILVS 241
             ::.:.:.:.::|...:.:.||:|...|..:..::..:..||.. |:..|.|:..|.|::|...:
Yeast   179 -LLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIRTLKSVVSC-DIECHFHNDTGCAIANAYTA 241

  Fly   242 LDYGIRVVDSSVSGLG 257
            |:.|.|::|.||.|:|
Yeast   242 LEGGARLIDVSVLGIG 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmgcl	NP_609089.1	DRE_TIM_HMGL	28..300	CDD:163676	55/246 (22%)
LYS21	NP_010151.1	DRE_TIM_HCS	37..298	CDD:163685	55/248 (22%)