Protein Alignment Hmgcl and hmgcl

DIOPT Version :9

• Sequence 1: NP_001285696.1
• Gene: Hmgcl / 33978
• FlyBaseID: FBgn0031877
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_957509.1
• Gene: hmgcl / 394190
• ZFINID: ZDB-GENE-040426-958
• Length: 340
• Species: Danio rerio
• Alignment Length: 317
• Identity: 195/317 - (61%)
• Similarity: 247/317 - (77%)
• Gaps: 13/317 - (4%)

  Fly     3 SAPIRSILALTAKRTAVTSAANQ-----VRIVEVGPRDGLQNEPKLLPAATKIELINQLSETGLR 62
            ||.|||:        :|::||:|     |:|||||||||||||..::|...||.||:.|||.||.
Zfish    28 SALIRSV--------SVSAAASQALPERVKIVEVGPRDGLQNEKTIVPTEVKIRLIDMLSEAGLP 84

  Fly    63 TIEATSFVSAKWVPQMGDNAEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAF 127
            .||||||||.||||||.|..||::|:.|..|::|||||||||||::|::|||:|||:|||||:.|
Zfish    85 VIEATSFVSPKWVPQMADQEEVMRGLHKKPGVNYPVLTPNLKGFQAAVKAGAKEVAIFGAASELF 149

  Fly   128 SLKNVNCTAAEAIERFKPVLKAAQKHGVRVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMGCYE 192
            |.||:||:..|::.||:.|:.||::.||.||||||.|:||||||.|:||.|.:|.:.||.|||||
Zfish   150 SKKNINCSVEESLVRFEEVMTAAKQEGVSVRGYVSCVLGCPYEGKVSPSKVAEVAKRLYSMGCYE 214

  Fly   193 ISLGDTIGVGTPGTMRRMLDEVTKVVPAKDLAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLG 257
            :||||||||||||.|..||:.|.|.:|.:.|||||||||||||:||||:|..|:.||||||:|||
Zfish   215 VSLGDTIGVGTPGGMTEMLNAVKKELPVEALAVHCHDTYGQALANILVALQNGVSVVDSSVAGLG 279

  Fly   258 GCPYAKGASGNAATEDVVYLLHGMGLDTGVNLDKLIQVGRYICTELGRTSESKVNRA 314
            |||||:|||||.|||||||:|||:|:.|||:|.:|:..|.:||..:.|.:.|||.:|
Zfish   280 GCPYAQGASGNVATEDVVYMLHGLGIHTGVDLPRLLDAGSFICHSINRRTNSKVAQA 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmgcl	NP_001285696.1	HMGL-like	25..299	CDD:279072	180/278 (65%)
		DRE_TIM_HMGL	28..300	CDD:163676	178/271 (66%)
hmgcl	NP_957509.1	HMGL-like	47..321	CDD:279072	179/273 (66%)
		DRE_TIM_HMGL	50..323	CDD:163676	179/272 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	380	1.000	Domainoid score	I801
eggNOG	1	0.900	-	-		E1_COG0119
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H159
Inparanoid	1	1.050	395	1.000	Inparanoid score	I1922
OMA	1	1.010	-	-		QHG55007
OrthoDB	1	1.010	-	-		D1029775at2759
OrthoFinder	1	1.000	-	-		FOG0002283
OrthoInspector	1	1.000	-	-		otm25385
orthoMCL	1	0.900	-	-		OOG6_101527
Panther	1	1.100	-	-	LDO	PTHR42738
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4186
SonicParanoid	1	1.000	-	-		X1709
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.870