Protein Alignment Hmgcl and hmgcll1

DIOPT Version :10

• Sequence 1: NP_609089.1
• Gene: Hmgcl / 33978
• FlyBaseID: FBgn0031877
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: XP_017949568.1
• Gene: hmgcll1 / 100497263
• XenbaseID: XB-GENE-952336
• Length: 335
• Species: Xenopus tropicalis
• Alignment Length: 289
• Identity: 180/289 - (62%)
• Similarity: 229/289 - (79%)
• Gaps: 0/289 - (0%)

  Fly    26 VRIVEVGPRDGLQNEPKLLPAATKIELINQLSETGLRTIEATSFVSAKWVPQMGDNAEVLKGIRK 90
            |:|||||||||||||.|.:|...|||.|::||:|||..||.|||||:||||||.|:.||::.|:|
 Frog    43 VKIVEVGPRDGLQNEKKFVPTDVKIEFIDRLSDTGLPAIEVTSFVSSKWVPQMSDHTEVMQSIKK 107

  Fly    91 VTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAEAIERFKPVLKAAQKHGV 155
            ..|:.|||||||:|||.||:.|||.||:||||||:.|:..|:||:..|::.||:.::|||....|
 Frog   108 HPGVCYPVLTPNIKGFHSAIAAGATEVSVFGAASETFNRMNINCSVEESLARFEDIIKAASNIKV 172

  Fly   156 RVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMGCYEISLGDTIGVGTPGTMRRMLDEVTKVVPA 220
            .||||||..:||||||.:|.|.|.:|.:.||.||||||||||||||||||:||:||:.|.|.||.
 Frog   173 PVRGYVSCALGCPYEGNIATSKVSEVSKRLYSMGCYEISLGDTIGVGTPGSMRKMLESVIKEVPV 237

  Fly   221 KDLAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLGGCPYAKGASGNAATEDVVYLLHGMGLDT 285
            ..|||||||||||||:|||.::..|:.|||.:|:|||||||||||:||.|||||:|:|:|:|:.|
 Frog   238 SALAVHCHDTYGQALANILTAIQMGVSVVDCAVAGLGGCPYAKGATGNVATEDVIYMLNGLGIHT 302

  Fly   286 GVNLDKLIQVGRYICTELGRTSESKVNRA 314
            ||||.|:::.|.:||:.|.|.:.|||.:|
 Frog   303 GVNLSKVMEAGHFICSALDRNTNSKVAQA 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmgcl	NP_609089.1	DRE_TIM_HMGL	28..300	CDD:163676	171/271 (63%)
hmgcll1	XP_017949568.1	TIM-like beta/alpha barrel domains	24..331	CDD:473867	179/287 (62%)