DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atac1 and DNAJC1

DIOPT Version :9

Sequence 1:	NP_609088.1	Gene:	Atac1 / 33977	FlyBaseID:	FBgn0031876	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_071760.2	Gene:	DNAJC1 / 64215	HGNCID:	20090	Length:	554	Species:	Homo sapiens

Alignment Length:	269	Identity:	59/269 - (21%)
Similarity:	101/269 - (37%)	Gaps:	74/269 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 PDLPTLSP------NDEEGGTN--ETPTDASSWTQEANKNRDRSNGRSENFNRLWTNEEQSRLEQ 145
            |:.|..:|      ...:.||:  |.......|.:  |:||.:.....|     ||.|:.|:|.:
Human   283 PEFPVYTPLETTYIQSYDHGTSIEEIEEQMDDWLE--NRNRTQKKQAPE-----WTEEDLSQLTR 340

  Fly   146 LLIQYP---PEEVEMRRFGKIAKALGNRTAQQVYSRVQKYFQKLHDAGMPVPGRIPKHRRPGLSK 207
            .::::|   |     .|:.|||..|| |:...|.::.    ::|.|:....||.:.........:
Human   341 SMVKFPGGTP-----GRWEKIAHELG-RSVTDVTTKA----KQLKDSVTCSPGMVRLSELKSTVQ 395

  Fly   208 PKIKLRKSTFFPAHNISLQ------MPEDDFTFDDLRIPSPASD---------MLLMPASKIEPK 257
            ....::.:|..|...|:.:      ..|::...|.....:.|:|         .||...:|.||:
Human   396 NSRPIKTATTLPDDMITQREDAEGVAAEEEQEGDSGEQETGATDARPRRRKPARLLEATAKPEPE 460

  Fly   258 IES---EYMDADL-------NAESKRK-------------QELCLKLLSAIQDEKREMEDGYEPD 299
            .:|   ...|.|:       :.||.||             |:..|:|  |:|...|...|.::
Human   461 EKSRAKRQKDFDIAEQNESSDEESLRKERARSAEEPWTQNQQKLLEL--ALQQYPRGSSDRWD-- 521

  Fly   300 LLAAKCAEC 308
                |.|.|
Human   522 ----KIARC 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atac1	NP_609088.1	SANT	135..185	CDD:197842	15/52 (29%)
Atac1	NP_609088.1	SANT	135..183	CDD:238096	15/50 (30%)
DNAJC1	NP_071760.2	DnaJ	65..126	CDD:278647
		SANT	329..375	CDD:238096	16/60 (27%)
		SANT	495..544	CDD:197842	10/40 (25%)
		SANT	496..543	CDD:238096	10/39 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900