Protein Alignment CG3430 and MCMBP

DIOPT Version :10

• Sequence 1: NP_542438.1
• Gene: CG3430 / 33976
• FlyBaseID: FBgn0031875
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_079110.1
• Gene: MCMBP / 79892
• HGNCID: 25782
• Length: 642
• Species: Homo sapiens
• Alignment Length: 664
• Identity: 236/664 - (35%)
• Similarity: 351/664 - (52%)
• Gaps: 102/664 - (15%)

  Fly     1 MPCAMELPSTPDELAAQQADSAA--------------LKDLLKDPS--RWHSIPLLNYTPLHKLK 49
            |||..:..|.|  |...|...|.              .|:.||:.:  :|  :|.||..|||.||
Human     1 MPCGEDWLSHP--LGIVQGFFAQNGVNPDWEKKVIEYFKEKLKENNAPKW--VPSLNEVPLHYLK 61

  Fly    50 DQTLVRFRGMIQDMMDPEIYLERYEVKSADGSKRVQE-GKYRDCLKIANGEVIDYNADGNVHGER 113
            ..:.|:||.|||||.|||.|:..||..:.:....|.. |||||..:....:.:|.|:..|...||
Human    62 PNSFVKFRCMIQDMFDPEFYMGVYETVNQNTKAHVLHFGKYRDVAECGPQQELDLNSPRNTTLER 126

  Fly   114 RTMFVVSVPGLNDWSKE-----HEKLCCPQIDLASLGQSPSSAKKRTIVGEEEAMDVDVASETTF 173
            :|.:.|.|||.:.|.||     ::....|     |...:||..|:    ..|:..|:|:....
Human   127 QTFYCVPVPGESTWVKEAYVNANQARVSP-----STSYTPSRHKR----SYEDDDDMDLQPNK-- 180

  Fly   174 KRPCLKEIQKD-----------------SEP--------VGASKSSV-LGSDYLINSPLPDRPSM 212
                    |||                 .||        .|...:|: |.|.:.:|.|||.....
Human   181 --------QKDQHAGARQAGSVGGLQWCGEPKRLETEASTGQQLNSLNLSSPFDLNFPLPGEKGP 237

  Fly   213 ACMVKVYEEFDTYQLNSLVDFVGFLSVDASLD---------AATLEIDDCENLSELQAAH-PSPF 267
            ||:|||||::|.:::|.:::..|.||||..|.         :|.|:..:|.:.:|.|..| |...
Human   238 ACLVKVYEDWDCFKVNDILELYGILSVDPVLSILNNDERDASALLDPMECTDTAEEQRVHSPPAS 302

  Fly   268 LIPRLHAFGVQVLPHANPLLDKSL-RQPTEICE--ETYPTHLA-VHKDLRMLLKLCLFDDDLAAE 328
            |:||:|....|.|.|.||||...| ::.::.|:  .::.:.|: |..:|...|...|..|.||||
Human   303 LVPRIHVILAQKLQHINPLLPACLNKEESKTCKFVSSFMSELSPVRAELLGFLTHALLGDSLAAE 367

  Fly   329 YLLSHLISTVYSRSEMQSIGKFALNLCNLPKNCEAYATKLYQILELLLPASHYMPMTLVTLNTAA 393
            ||:.|||||||:|.::..:|||.:||...|:| ..:...||:|::.|:|||..:.||:..:|...
Human   368 YLILHLISTVYTRRDVLPLGKFTVNLSGCPRN-STFTEHLYRIIQHLVPASFRLQMTIENMNHLK 431

  Fly   394 FAPKKDYETNKLVSGVLQLAPHTHLVLDETCMQQGKLEANGVHAVQHLAHLINNQELKCDFQYYQ 458
            |.|.|||..|:||||:|||..:|.||:|||.::||:|:..|||.|..|::||..|::..||.|:|
Human   432 FIPHKDYTANRLVSGLLQLPSNTSLVIDETLLEQGQLDTPGVHNVTALSNLITWQKVDYDFSYHQ 496

  Fly   459 IDYQANIPVLVLSEGRSMLPSDF-------VLPINADSKAVELVDESLKAAHHYLQPSRLQQFRK 516
            :::..||.|.:.|||||:||:|.       ::|.|.:    |.::..|.|    :.||.|.:||.
Human   497 MEFPCNINVFITSEGRSLLPADCQIHLQPQLIPPNME----EYMNSLLSA----VLPSVLNKFRI 553

  Fly   517 YLTTARTSGFNVSEEHTEMIQQDFVDMRKANVKS-NADDLHGLLVLSRLLGIARGKDTLDKETWQ 580
            |||..|...:::|:|.|:.::.|||:|||.:.:| .|||||.|||::|.|.::.|:.||.:|.|.
Human   554 YLTLLRFLEYSISDEITKAVEDDFVEMRKNDPQSITADDLHQLLVVARCLSLSAGQTTLSRERWL 618

  Fly   581 LATEFEAKRRQRIQ 594
            .|.:.|:.||.|:|
Human   619 RAKQLESLRRTRLQ 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3430	NP_542438.1	MCM_bind	24..590	CDD:462870	224/621 (36%)
MCMBP	NP_079110.1	MCM_bind	36..628	CDD:462870	224/621 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..197		11/64 (17%)