DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13775 and Zbed6

DIOPT Version :9

Sequence 1:	NP_001285694.1	Gene:	CG13775 / 33975	FlyBaseID:	FBgn0031874	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	XP_038947242.1	Gene:	Zbed6 / 103693666	RGDID:	9238526	Length:	983	Species:	Rattus norvegicus

Alignment Length:	751	Identity:	153/751 - (20%)
Similarity:	277/751 - (36%)	Gaps:	206/751 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KKSNVWQYFYKTSGTV--ATCLLCNRNYSRRGR-----GTTCLRNHLKSKHP------------- 48
            |.|.||.:||.....:  |.|.:|.|:.| |||     ||:.|:.||::.||
  Rat   266 KTSAVWNFFYTDPQHISRAVCNICKRSVS-RGRPGSHLGTSTLQRHLQATHPIHWAVANKDSGAI 329

  Fly    49 ----PEFLSLSGDIKYLDLVKSEISIGSPQHPTAQLELNLHETDSDP-LDTEDISYS-------- 100
                .|..:.|||: ..|.:..|.|.|| |..||:...:..:||..| |:.|:.|.|
  Rat   330 GNGLDETETESGDL-LNDTLHGEKSSGS-QDLTAEDLSDSDDTDEPPVLEVENRSESPIPVAEQD 392

  Fly   101 -------------KRCDEKLALMLLN----------HSFEFIEGPGFVNFIRTLQPRYTIQPRSY 142
                         ..|::..:..:..          |.:.:...|.|..|::.:.|.|.:...:|
  Rat   393 NLAHTQERETTTDTHCEDAASSQISQAVIQMIVEDLHPYNYFSTPAFQRFLQIVAPDYRLPSETY 457

  Fly   143 Y-------------EKIL--CEDIQ-RKMHQHLKQQVDLLDAISLSTSLWRGDKGEGLLSLSCSG 191
            :             |||.  .|::| :|:|              |:..:|..|.......::...
  Rat   458 FFTKAVPQLYDSVREKIFLTLENVQSQKIH--------------LTVDIWTHDPSTDYFIVTVHW 508

  Fly   192 ISRDFQTHRLMLKCEALNYESTSKLA-------CCIRD-----------------LVPSLAI-EV 231
            :|  .:|..........|:...:.|.       |.|.:                 |:||..: :.
  Rat   509 VS--LETASSPSNGGTPNFRKWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLIPSFIVSDN 571

  Fly   232 PKEKIHCVIRDEMTALPGSLPDCSVHRLQMCVRFALQSNELLQNLSSKCKQIVDHFASSKMA--- 293
            ....:|.:.....|.:|     |.:|.|.:.::.....::.::|:....::...||:.|..|
  Rat   572 SSNVVHAIKGGGFTHVP-----CFLHCLNIVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQI 631

  Fly   294 -----NDHLKFIQEIRLTRDPCTLTPYDPCQWNSAFQMMSSVFRMKDALSLYCEEYSL-----VQ 348
                 |||.  :....|.:|       :...|.|.|.|:..:..     ..|...:||     |.
  Rat   632 LQEFQNDHQ--LPWKNLKQD-------ETGHWISTFYMLKWLLE-----HCYSVHHSLGRASGVV 682

  Fly   349 IYPDEWIEIDLCSKVMQPCEETIKIWSNPSTTTSSVIPLVAALRDSLR-----------TDVHNF 402
            :...:|..:.....:::|.||..:..|..:|..:.|:|::..|..||:           |...|.
  Rat   683 LTSLQWTLMTYVCDILKPFEEATQRVSVKTTGLNQVLPIIHHLLFSLQRLREDFQVRGITQALNL 747

  Fly   403 VSSVTICSFARKLLEELEMKFAHITSDINFLMATYLDPRYKQA---FF-----TEREEQLVANEV 459
            |.|:::...:..||..: :|..|.      ::||.|||.:|.:   ||     .|..:|::|.||
  Rat   748 VDSLSLKLESDALLSAM-LKSKHC------ILATLLDPCFKNSLEDFFPQGADLETYKQILAEEV 805

  Fly   460 LLQLAGVPEDC-----NGQPPLKIIKVSSTSSQKNESKIDSILDSILTTGTTNTQQPNTSMGSQS 519
            ...:...|..|     ....||..:...|.:|.|..:.....:||        :...:.::||:|
  Rat   806 CNYMESSPGACQIASSEASGPLVRLGTDSFTSIKEGTSSAGSMDS--------SAADSVAIGSRS 862

  Fly   520 QIKNLLYLYNSE------------PRIDRNMDPLIWWRSNIK-YISLYGIVRKFLSAPAASVVSE 571
                  :|:.|.            ..:....|||::|:..:. :.:|..:..::||.|..|..||
  Rat   863 ------FLFPSAVAVVDEYFKEKYSELSGGDDPLVYWQRKVSIWPALTQVAIQYLSCPMCSWQSE 921

  Fly   572 GLFRKSTHLYFDMQAGLSPESASKMLLMKANFSFSN 607
            .:|..::|.:......:..::..:::.:|.|....|
  Rat   922 CMFTTNSHFHPKQIMNMDFDNIEQLIFLKMNLENVN 957

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13775	NP_001285694.1	zf-BED	6..48	CDD:280965	18/48 (38%)
CG13775	NP_001285694.1	Dimer_Tnp_hAT	525..603	CDD:283379	16/90 (18%)
Zbed6	XP_038947242.1	ZnF_BED	135..182	CDD:214746
		ZnF_BED	270..316	CDD:214746	17/46 (37%)
		Dimer_Tnp_hAT	873..953	CDD:399013	14/79 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223749at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010