DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13775 and zbed6cl

DIOPT Version :9

Sequence 1:	NP_001285694.1	Gene:	CG13775 / 33975	FlyBaseID:	FBgn0031874	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	XP_004919610.2	Gene:	zbed6cl / 101730718	XenbaseID:	XB-GENE-22065650	Length:	1050	Species:	Xenopus tropicalis

Alignment Length:	761	Identity:	158/761 - (20%)
Similarity:	285/761 - (37%)	Gaps:	231/761 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KKKSNVWQYFY--KTSGTVATCLLCNRNYSRRGR-----GTTCLRNHLKSKHPPEFLSLSGDI-- 58
            |..|.|||:|.  :|:...|.|.||..:.| ||:     ||:.|..||:.|||.|:  ..|.|
Frog   297 KSTSAVWQFFSIDRTNICRAICKLCQLSVS-RGKQGGHFGTSALMRHLEGKHPIEW--ARGKINK 358

  Fly    59 ------------------KYLDLVKSEISI-----GSPQH--------------PTAQLELNLHE 86
                              :.|:.:.|:..:     |||.|              ||..:.:..:.
Frog   359 PKGHNVIEVDEDEEDETDEPLEQIYSQPQVLLGLYGSPTHYDTYSTETSDVMTPPTHAMPMEYNT 423

  Fly    87 TDSDPLDTEDI--SYSKRCDEKLALMLL-----------NH-------------------SFEFI 119
            .|::| ..|:|  .:|...:||.||.|.           ||                   .:.||
Frog   424 EDTEP-TKEEIRDDFSVTTEEKPALPLSEDLNIKGKYAPNHPKAQSWNRNIAELVCGMALPYSFI 487

  Fly   120 EGPGFVNFIRTLQPRYTIQPRSYYE--------KILCEDIQRKM------HQHLKQQVDLLDAIS 170
            ....|..|:....|:|.:..:|::.        :.:||.:..::      |.|
Frog   488 TSKAFKKFMARADPKYCVPSKSFFSAKAVPQLYEAVCEKVMSELKRSECAHVH------------ 540

  Fly   171 LSTSLWRGDKGEGLLSLSCSGISRDF---QTHRLMLKCEALNYESTSKLACCIRDLVPSLAIEVP 232
            |:|.:|.|            |:|.|:   ..|..:|..|.|..........|.:..        |
Frog   541 LTTHVWSG------------GLSVDYLALTAHWSVLNPEDLQSIQRKNAVLCTKGF--------P 585

  Fly   233 KEKIHCVIRDEM----------TAL-PG--------------------SLPDCSVHRLQMCVRFA 266
            |:.|...|:.|:          .|| ||                    |:| |..|.|.:.|...
Frog   586 KDYIDGSIQQELIRQMNLWLSPNALSPGFFISSGNFNLIHAIKSANFNSIP-CFTHTLNLLVMDF 649

  Fly   267 LQSNELLQNLSSKCKQIVDHFASSKMANDHLKFIQ-EIRLTRDPC---TLTPYDPCQWNSAFQMM 327
            ||:|..:.::....:::..||..|..|...|..:| :..|.:.|.   || |:    |.|.|.|:
Frog   650 LQNNHYISSMLEVARKVCSHFIHSARARRILSELQFQNHLPKQPLKSETL-PH----WTSTFYML 709

  Fly   328 SSVFRMKDALSLYCEEYSL----VQIYPDEWIEIDLCSKVMQPCEETIKIWSNPSTTTSSVIPLV 388
            ..:...:.|:..|...:.|    :::....|..:.....::||.|...:..:...:..|.|:|.|
Frog   710 QRLLEQQRAIEEYLGSHKLETAELRLTSSNWSLMACLVDLLQPFEMVTREVNASGSCLSQVLPEV 774

  Fly   389 AALRDSLRTDVHNFVSSVTICSFARKLLEELEMKFAHITSD--IN-------FLMATYLDPRYK- 443
            ..|...|:....:|.|...:....  |.:...:||   :||  ||       ::::|.||||:|
Frog   775 RYLHIFLKQIRGHFESKGDVNGVV--LTDSFTLKF---SSDFGINEMFQREEYVVSTLLDPRFKG 834

  Fly   444 --QAFF-----TEREEQLVANEV--LLQLAGVP----EDCNGQPPLKIIKVSSTSSQKNESKID- 494
              :|..     .:..:|::..:|  ::..:..|    :|.:.:|.    :::|.....:|..:|
Frog   835 RIEAILPPGSDIDHWKQILVKKVKEIMSSSSRPVSHLKDSSSEPD----RLASKHYHLDEGGVDS 895

  Fly   495 ----------------SILDSILTTGTTNTQQPNTSMGSQSQIKNLL---YLYNSEPRIDRNMDP 540
                            |:::.:.:.|...::....|:.::|....::   ||.::: .|....||
Frog   896 PRRRTTVAPPLIQKEKSLIEHLESVGLLASKSTGASLSTESHSACVMVEKYLQDNQ-TIGAKEDP 959

  Fly   541 LIWW-RSNIKYISLYGIVRKFLSAPAASVVSEGLFRKSTHLYFDMQ 585
            |::| :....:.:|..:...:|:.|.:|:.::.:| .|...:.|||
Frog   960 LVYWEKRKCLWPALTKLAFMYLTCPPSSIFAQRVF-SSPSKHGDMQ 1004

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13775	NP_001285694.1	zf-BED	6..48	CDD:280965	19/48 (40%)
CG13775	NP_001285694.1	Dimer_Tnp_hAT	525..603	CDD:283379	16/65 (25%)
zbed6cl	XP_004919610.2	ZnF_BED	89..138	CDD:214746
		ZnF_BED	302..350	CDD:214746	20/48 (42%)
		Dimer_Tnp_hAT	944..>1000	CDD:399013	13/57 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7185
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I4425
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223749at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060