DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13775 and si:dkey-109j17.5

DIOPT Version :9

Sequence 1:	NP_001285694.1	Gene:	CG13775 / 33975	FlyBaseID:	FBgn0031874	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	XP_002666517.2	Gene:	si:dkey-109j17.5 / 100316941	ZFINID:	ZDB-GENE-090313-173	Length:	636	Species:	Danio rerio

Alignment Length:	712	Identity:	142/712 - (19%)
Similarity:	252/712 - (35%)	Gaps:	193/712 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SKKKSNVWQYF----YKTSGTV-ATCLLCNRNYSRRGRGTTCLRNHLKSKHP---PEFLSLSGDI 58
            ||.:.::..||    ...:|.: :.|..|......:...|:....|||.||.   .||:. ..|:
Zfish     3 SKSRVSILDYFNIVCEGENGKIESNCKACGTRIQAKRTVTSNFVTHLKRKHQAMYDEFVR-KKDV 66

  Fly    59 KYLDLVKSEISIGSPQ-HPTAQLELNLHETD-SDPLDTEDISYSKRCDEKLALMLLN--HSFEFI 119
            |...:   :...|.|. ....|....|::.| |||..:       ...|.:|.|::.  ...:.:
Zfish    67 KREAM---QTCTGPPSGRMIPQTAAGLNKFDYSDPRQS-------LISEAIAKMIIRDLQPPQIV 121

  Fly   120 EGPGFVNFIRTLQPRYTIQPRSYYEKILCEDIQRKMHQHLKQQVDL--------LDAISLSTSLW 176
            |..||...::.|:|||.        .:.|..||:::......||.|        .::.|::..||
Zfish   122 EYEGFRELLQLLEPRYI--------PVQCHYIQQQLLPAYVSQVQLAAKQALKGAESCSVTLDLW 178

  Fly   177 R-----GDKGEGLLSLSCSGISRDFQTHRLMLKCEAL------------------NYESTSKLAC 218
            |     ...|.|.|.::|..|:.|:.....:|.|..|                  ::..|.|:..
Zfish   179 RSSSVGNSSGAGYLGVTCHFINADWHIRSALLACLPLPDHSNTQQMLSEFDEISESHGITGKVFR 243

  Fly   219 CIRDLVPSLAIEVPKEKIHCVIRDEMTALPG---------------------------------- 249
            .:.||:|            |..|.:. .|||
Zfish   244 VVADLLP------------CESRSDF-RLPGFSLIGNGEEDEEGEEDGSNGDPGEGESKEGISSN 295

  Fly   250 ------------SLPDCSVHRLQMCVR----------FALQSNELLQN---LSSKCKQIVDHFAS 289
                        |..||....|..|::          ..|....||.|   .:...:::|..|.|
Zfish   296 EYHRSLDQCLGRSRIDCFARLLAQCIKEGVCASPHVSLPLNKASLLYNYIIATVAPEKLVQVFGS 360

  Fly   290 SKMANDHLKFIQEIRLTRDPCTLTPYDPCQWNSAFQMMSSVFRMKDALSLYCEEYSLVQIYPDEW 354
            |  ||                ...|....:||...:::..:....|.|....:...||....::.
Zfish   361 S--AN----------------WQRPSSTDKWNDQLKILRQMVDSMDFLEDIVDRNDLVLGNLEKE 407

  Fly   355 IEIDLCSKVMQPCEE-TIKIWSNPSTTTSSVIPLVAALRDSLRTDVHNFVSSVTICSFARKLLEE 418
            :..:|. :|::|.|| :..:..:...:.|..:|.|..||..|...|.:..|.:.:     .|.:.
Zfish   408 LLRELV-EVLEPFEEASDMVQGDKHVSISLALPCVLGLRKHLAEVVTHQCSGIVM-----GLSQA 466

  Fly   419 LEMKFAHITSDINFLMATYLDPRYKQAFFTERE--EQLVANEV---LLQLAGVPEDCNGQP-PLK 477
            |:.:.|.|..|..::.||.|||::|.::.::.:  :|::..||   ...|:.:......|| |.|
Zfish   467 LDRRLAGILEDPLYVTATTLDPQFKLSWSSDSDWHKQVLLEEVEKHTRTLSPIEHYSETQPSPSK 531

  Fly   478 IIKVSSTSSQKNESKIDSILDSILTTGTTNTQQPNTSMGSQSQIKNLLYLYNSEPRIDRNMDPLI 542
            ..|:.|...|:...:..::...:.|                       ||: .||   .:.|||.
Zfish   532 RCKLFSFIKQRPTMQAKTVEQELST-----------------------YLH-EEP---TDEDPLQ 569

  Fly   543 WW-RSNIKYISLYGIVRKFLSAPAASVVSEGLFRKSTHLYFDMQAGLSPESASKMLLMKANF 603
            :| |.:|.:..|..:.:|..:.||.:...:.:|...:......|....|::...::.:|||:
Zfish   570 YWKRKSIDFPLLSQVAKKVFTVPATTTSVDQIFNTVSKTLRPDQCRFLPKNLDTLIYLKANY 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13775	NP_001285694.1	zf-BED	6..48	CDD:280965	10/46 (22%)
CG13775	NP_001285694.1	Dimer_Tnp_hAT	525..603	CDD:283379	19/78 (24%)
si:dkey-109j17.5	XP_002666517.2	ZnF_BED	9..55	CDD:214746	11/45 (24%)
si:dkey-109j17.5	XP_002666517.2	Dimer_Tnp_hAT	553..631	CDD:310361	20/104 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223749at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920