Protein Alignment SA1 and stag1a

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: NP_001349269.1
• Gene: stag1a / 564533
• ZFINID: ZDB-GENE-070912-448
• Length: 1258
• Species: Danio rerio
• Alignment Length: 1131
• Identity: 511/1131 - (45%)
• Similarity: 718/1131 - (63%)
• Gaps: 91/1131 - (8%)

  Fly    29 ESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDFFAPIARKRKTPATRKGPTERKERVERPRK 93
            :|..|..|.:..|:.|              ||..|  ..|.:||..|.  :.|...|    :|||
Zfish    14 DSGQDTVSLSMSMSEL--------------DDPGD--GKIKKKRGRPG--RPPAANK----KPRK 56

  Fly    94 EP-------VDKGHHERIDSEREITTDENSLYYIVRHSKNPIASIVDQWIEQYKANRETALVALM 151
            .|       |.:|......|::....|..:|:.:|:..|:.:.|:||.|||.||.:|:.||:.|:
Zfish    57 SPSEKGFMAVQRGRKANGISQQNGEGDPVTLFEVVKQGKSAMQSVVDDWIESYKQDRDLALLDLI 121

  Fly   152 QFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRKFKNNFCDFVQTLV 216
            .|||..|||||.:..::...:.:..|||:|||||||:||:|||.:||..|:||:.|||:|:..|:
Zfish   122 NFFIQCSGCKGTVRIEMFRNMQNAEIIRKMTEEFDEDSGDYPLTISGPLWKKFRYNFCEFICVLI 186

  Fly   217 KQCQYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLVSNNFDNAAKQF 281
            :|||||||||:::||.|||||||||||||||||||:||||||||||||:|||.:|.|.||..:|:
Zfish   187 RQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINQDNTQRQY 251

  Fly   282 EAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIG 346
            ||||.|...:||:::|:.|:.||.||:||.|||::|:..:||.:|||||||::.:|||||:.|||
Zfish   252 EAERSKIVGKRATEKLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIG 316

  Fly   347 IWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDELKGKLELFTSKFKDRIVAM 411
            :||:.|...||:||||||:||||||:.|||||:||::|..||...||..||||||::||||||:|
Zfish   317 VWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQNLYTNRELFPKLELFTNRFKDRIVSM 381

  Fly   412 TLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAEFLNVRLF--HLTA 474
            |||||::|:|.|::||..||:...:.|:::|||.||.||||:||.||.||.|||:.:||  | ..
Zfish   382 TLDKEYDVAVEAIRLVTLILQGSEDALSNEDCENVYHLVYSAHRPVAVAAGEFLHRKLFSRH-DP 445

  Fly   475 DMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFIDSN-DMVRDWECMTDLLLEEP 538
            ..||...||.....||..|:|.||.||:|||||||.||||||..:|: ::::||||||:||||||
Zfish   446 QAEEALAKRRGRSSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEP 510

  Fly   539 GPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVT 603
            ...||||.::|||:|||:.|.:::|:|....||||.:.:: .|:|||.|...|:|.|||||||:.
Zfish   511 VQGEEVLADRQESSLIELTVCTIRQAAEAHPPVGRGTGKR-VLTAKERKMQIDDKNKLTEHFIMA 574

  Fly   604 LPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTGREVLETCAKT 668
            ||.||.|||.||||:||||.:||||||::|:..|.|.:|.|||.:|..|:..||..||||.|:||
Zfish   575 LPMLLSKYQTDSEKVANLLQIPQYFDLDVYSAGRMEKHLDALLKQIKFVVEKHTDTEVLEACSKT 639

  Fly   669 LECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNITITLKVLSIL 733
            ...||:|......|.:||||.:|:...:::..::||   |:|..|..::|||||:..|||.|:..
Zfish   640 YSILCSEEYTIMNRVDIARSQLIDELADRFNHSVEE---LLQAGEEADDDDIYNVLSTLKRLTAF 701

  Fly   734 YSSHNLNPWELFKSLFQ----DVEEAQSKENIDRCLPNEALVYCIEACYFSISWGLQYVENECES 794
            :::|:|..|:.|.:.::    .:|:..        :|.:..|..::..::||.|.|
Zfish   702 HNAHDLTRWDFFGNCYRLLRTGIEQGS--------MPEQIAVQALQCSHYSILWQL--------- 749

  Fly   795 VNVTE------VVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEIEH 853
            |.:||      .:..||..:.:|:..|.:...:..| .::|.|:..:||||:|||.:|.....|.
Zfish   750 VKITEGAPSKDDLLALRRVVKSFLAICQQCLSNVNT-PVKEQAFMLLCDLLMIFSHQLTTGSREG 813

  Fly   854 IRGLEY--KSRMDEHLILDNFVQHYVF--------SLKQDVAQDETRIEELHKKRNFLACYCKLV 908
            ::.|.:  ...:...|:  ||:..:||        |::.|...:..:||.|||:||.||.:.||:
Zfish   814 LQPLVFIPDGTLQNELL--NFILDHVFIDQDDENQSIEGDEEDEANKIEALHKRRNLLAAFSKLI 876

  Fly   909 VYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSL-QEQSED 972
            :|:||....||.|||:|:|.|||||||||.||.|.|:.:|:..|.||:|||..:|..| |:|..:
Zfish   877 IYDIIDMPAAADIFKHYMKYYNDYGDIIKETLSKTRQTDKILCAKTLILSLQQLFNELIQDQGPN 941

  Fly   973 GIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAAN-KEPDDPVRAPTRLLFL 1036
              :.::|.....:||||:|||||||.|.||.||:||.:|:.||.||.. :.|......|..|.||
Zfish   942 --LDRTSSHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNPKGAEYPPPNLAFL 1004

  Fly  1037 EVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLL-HGETDQAPV-----A 1095
            |||.||:.|||:||||.:.::|:|.:...|...|.:.|.|||.|||||| .|:.|:..:     :
Zfish  1005 EVLCEFSSKLLRQDKKTVHAYLEKFMTEQMMERREDIWLPLISYRNSLLTGGDEDRMSITSGSSS 1069

  Fly  1096 SKRAYTRKRRD----HDEEEEEEEDE 1117
            ||....|.::.    |.:..|||..|
Zfish  1070 SKAGSIRSKKGRPPLHKKRIEEESME 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	198/366 (54%)
		STAG	190..303	CDD:462502	73/112 (65%)
stag1a	NP_001349269.1	IRR1	105..>398	CDD:227824	179/292 (61%)
		STAG	160..273	CDD:462502	73/112 (65%)