Protein Alignment SA1 and Stag1

DIOPT Version :10

• Sequence 1: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Sequence 2: NP_001420738.1
• Gene: Stag1 / 20842
• MGIID: 1098658
• Length: 1283
• Species: Mus musculus
• Alignment Length: 1210
• Identity: 516/1210 - (42%)
• Similarity: 738/1210 - (60%)
• Gaps: 158/1210 - (13%)

  Fly    25 DALNESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDFFAPIARKRKTPATRKGPTERKERVE 89
            |:.||:|:.:|:.::                 :::.|      :..|||.....:.|:..|
Mouse    11 DSTNETTAHSDAGSE-----------------LEETE------VKGKRKRGRPGRPPSTNK---- 48

  Fly    90 RPRKEPVDKGHHERIDS--------------EREITTDENSLYYIVRHSKNPIASIVDQWIEQYK 140
            :|||.|   |...||::              ::....|..:|:.:|:..|:.:.|:||.|||.||
Mouse    49 KPRKSP---GEKSRIEAGIRGAGRGRANGHPQQNGDGDPVTLFEVVKLGKSAMQSVVDDWIELYK 110

  Fly   141 ANRETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRKFK 205
            .:|:.||:.|:.|||..|||:|.:..::...:.:..|||:|||||||:||:|||.|.|.||:||:
Mouse   111 QDRDIALLDLINFFIQCSGCRGTVRIEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPQWKKFR 175

  Fly   206 NNFCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLV 270
            :|||:|:..|::|||||||||:::||.|||||||||||||||||||:||||||||||||:|||.:
Mouse   176 SNFCEFIGVLIRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNL 240

  Fly   271 SNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLP 335
            |.:.||..:|:||||.|...:||::||:.|:.||.||:||.|||::|:..:||.:|||||||::.
Mouse   241 SIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIA 305

  Fly   336 DIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDELKGKLELF 400
            :|||||:.|||:||:.|...||:||||||:||||||:.|||||:||::|..||...||..|||||
Mouse   306 EIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLELF 370

  Fly   401 TSKFK-------------------------DRIVAMTLDKEFEVSVHAVKLVISILKIHPEILAD 440
            |::||                         ||||:||||||::|:|.|::||..||....|.|::
Mouse   371 TNRFKTLQLHLFHCLDAVLHLRDCVLPLALDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSN 435

  Fly   441 KDCEIVYELVYSSHRGVAQAAAEFLNVRLF--HLTADMEETKTKRGKVRMPNTPLVRDLVQFFIE 503
            :|||.||.||||:||.||.||.|||:.:||  | ....||...||.....||..|:|.||.||:|
Mouse   436 EDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRH-DPQAEEALAKRRGRNSPNGNLIRMLVLFFLE 499

  Fly   504 SELHEHGAYLVDSFIDSN-DMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATG 567
            ||||||.||||||..:|: ::::||||||:||||||...||.:.::|||.|||:||.:::|:|..
Mouse   500 SELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEA 564

  Fly   568 EVPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNL 632
            ..||||.:.:: .|:|||.|...|::.|||||||:|||.||.||.||:||:||||.:||||||.:
Mouse   565 HPPVGRGTGKR-VLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEI 628

  Fly   633 YTTNRQEGNLQALLDRINQVMSMHTGREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNK 697
            |:|.|.|.:|.|||.:|..|:..|...:|||.|:||...||:|......|.:||||.:|:..|::
Mouse   629 YSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKTYSILCSEEYTIQNRVDIARSQLIDEFVDR 693

  Fly   698 YKDAIEEWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENID 762
            :..::|:   |:|..|..::|||||:..|||.|:..:::|:|..|:||.:.::.:     |..|:
Mouse   694 FNHSVED---LLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLL-----KTGIE 750

  Fly   763 R-CLPNEALVYCIEACYFSISWGLQYVENECESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQ 826
            . .:|.:.:|..::..::||.|.|..:.:...|   .|.:..||..:.:|:..|.:...:..| .
Mouse   751 HGAMPEQIVVQALQCSHYSILWQLVKITDGSPS---KEDLLVLRKTVKSFLAVCQQCLSNVNT-P 811

  Fly   827 IQEAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVF--------SLKQD 883
            ::|.|:..:||||:|||.:|.....|.::.|.:.........|.:||..:||        |::.|
Mouse   812 VKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGD 876

  Fly   884 VAQDETRIEELHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINK 948
            ...:..:||.|||:||.||.:.||::|:|:....||.|||:|:|.|||||||||.||.|.|:|:|
Mouse   877 EEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLSKTRQIDK 941

  Fly   949 VNFAMTLLLSLITVFKSL-QEQSEDGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHR 1012
            :..|.||:|||..:|..| |||..:  :.::|.....:||||:|||||||.|.||.||:||.:|:
Mouse   942 IQCAKTLILSLQQLFNELVQEQGPN--LDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHK 1004

  Fly  1013 GGIYFA----ANKEPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEE 1073
            .||.||    ..|..:.|   |..|.|||||:||:.|||:||||.:.|:|:|.:...|...|.:.
Mouse  1005 DGIEFAFKYQNQKGQEYP---PPNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDV 1066

  Fly  1074 WQPLILYRNSLL-HGETDQAPV-----ASKRAYTR---------KRRDHDEE------------- 1110
            |.|||.|||||: .||.|:..|     :||.:..|         ::|..||.
Mouse  1067 WLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRSKKGRPPLHRKRVEDESLDNTWLNRTDTMI 1131

  Fly  1111 ------------------------EEEEEDEEEH-NDPDY 1125
                                    |:.:|.|.|| ::||:
Mouse  1132 QTPGPLPTPQLTSTVLRENSRPMGEQIQEPESEHGSEPDF 1171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	197/398 (49%)
		STAG	190..303	CDD:462502	74/112 (66%)
Stag1	NP_001420738.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		16/77 (21%)
		IRR1	12..>376	CDD:227824	188/393 (48%)
		STAG	160..273	CDD:462502	74/112 (66%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1080..1173		17/92 (18%)