DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gas41 and gfl-1

DIOPT Version :9

Sequence 1:	NP_609086.1	Gene:	Gas41 / 33973	FlyBaseID:	FBgn0031873	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_502172.1	Gene:	gfl-1 / 187434	WormBaseID:	WBGene00001585	Length:	211	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	105/216 - (48%)
Similarity:	140/216 - (64%)	Gaps:	18/216 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RLKGVTIVKPIVYGNIARSFGKKREEDGHTHQWKVYLKPYFNEDMSIYVKKVHFKLHESYANPNR 75
            |:|...|||||||||.|..||.||:.|.|||||.|:||||..||.:.:::||.||||||||.|.|
Worm     7 RMKKKNIVKPIVYGNTATPFGYKRDSDQHTHQWTVFLKPYLIEDPTKWIRKVQFKLHESYAVPYR 71

  Fly    76 IVVKPPYEITETGWGEFEVIIKIYFNDQSERPVTCYHILKLFQSPVVDGELSSSTTMDTKKGLVS 140
            :|.|||||:|||||||||:.|:|||.|.:|:|:|.:|.|:|||..:   ||.|...:     :..
Worm    72 VVEKPPYEVTETGWGEFEIQIRIYFVDPNEKPITAFHYLRLFQPTI---ELPSGNQI-----VCM 128

  Fly   141 ESYEEIVFQEPTQILQHYLLLSEQSANGLLTHD----TDFEEKKTKTLDNIVNVKQK-VKGEIVT 200
            |.|:||:|||||  :|.|..|  |:::|.....    .|.|:.||:|.: :..|.|| :..||..
Worm   129 EFYDEIIFQEPT--VQMYKAL--QASDGKRPDKQAFLNDIEQVKTRTRE-LGEVAQKEIAAEIED 188

  Fly   201 LKDKLKLARETISKFKAELAK 221
            |::.||.|.:.|.|:..|||:
Worm   189 LRESLKDAHKMIVKYNTELAE 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gas41	NP_609086.1	YEATS	40..119	CDD:281374	50/78 (64%)
gfl-1	NP_502172.1	YEATS	36..115	CDD:281374	50/78 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159016
Domainoid	1	1.000	120	1.000	Domainoid score	I3577
eggNOG	1	0.900	-	-		E1_COG5033
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4760
Inparanoid	1	1.050	188	1.000	Inparanoid score	I2587
Isobase	1	0.950	-	0	Normalized mean entropy	S932
OMA	1	1.010	-	-		QHG52998
OrthoDB	1	1.010	-	-		D1482359at2759
OrthoFinder	1	1.000	-	-		FOG0003954
OrthoInspector	1	1.000	-	-		oto17686
orthoMCL	1	0.900	-	-		OOG6_102192
Panther	1	1.100	-	-	LDO	PTHR23195
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R29
SonicParanoid	1	1.000	-	-		X2721
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790