Protein Alignment ihog and BOC

DIOPT Version :9

• Sequence 1: NP_609085.1
• Gene: ihog / 33972
• FlyBaseID: FBgn0031872
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: XP_016862930.1
• Gene: BOC / 91653
• HGNCID: 17173
• Length: 1118
• Species: Homo sapiens
• Alignment Length: 1005
• Identity: 223/1005 - (22%)
• Similarity: 352/1005 - (35%)
• Gaps: 314/1005 - (31%)

  Fly    59 PESLVAPLGDEVVLECETSLQPERFEWSHRSSRSPGAGFKYLKTGTAKANVSQEAAISRLRVLVR 123
            |.|.|...|..|:|.|  .::|.|...:.|.:..             :.|.|.:|    |.||:.
Human    42 PASTVQKPGGTVILGC--VVEPPRMNVTWRLNGK-------------ELNGSDDA----LGVLIT 87

  Fly   124 PDTL----------GEYRCVGWFGPLVVTSTIARLELASTSLVDAQESESPLQW--RVSAGNSVL 176
            ..||          |.|:||.......|.|..|.:.||     :.|:.:..:|.  .|..||:.:
Human    88 HGTLVITALNNHTVGRYQCVARMPAGAVASVPATVTLA-----NLQDFKLDVQHVIEVDEGNTAV 147

  Fly   177 WSCGQQVQSNPSASWSYYRNGVEIKPEF---------IGTNGNLFLSNVSSESSGSYSCQATNPA 232
            .:| ...:|:|.|...|     .:|.|:         |..:|||.:.|.|.|..|.|.|.|.||.
Human   148 IAC-HLPESHPKAQVRY-----SVKQEWLEASRGNYLIMPSGNLQIVNASQEDEGMYKCAAYNPV 206

  Fly   233 SGERIQLPGSL-QLQVTPEQRSESKSPHLLRGQPSSQEITIREGSSLLLLCPGVGSPPPTVVWSS 296
            :.| ::..||. :|:|   :||.:::..::. .|.:|.|.:.:|.||:|.|...|.|||.|.|:.
Human   207 TQE-VKTSGSSDRLRV---RRSTAEAARIIY-PPEAQTIIVTKGQSLILECVASGIPPPRVTWAK 266

  Fly   297 PDVVGAVKNKRSKVFGHALEISNTRVNDAGTYICFQDNGV-RP-ALEHYIKVHVEQPPQIVRP-- 357
            ........||...:..:.| |..|...|:|||.|..|||| :| |......|.|.:||::...
Human   267 DGSSVTGYNKTRFLLSNLL-IDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELS 330

  Fly   358 ----PWADLTNEGDRLKLECKATGVPTPEIYWLLNGHSSIDDSEAELSNNFLILHSVLKRHAGYV 418
                ||      |...||.|:..|.|.|.:.||.|....|......||...|.:.|:.....|..
Human   331 QLVIPW------GQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRALRVLSMGPEDEGVY 389

  Fly   419 QCFARNRLGEHSAGTLLQV---------------------------------NPKQ--------- 441
            ||.|.|.:|  ||..::|:                                 ||:|
Human   390 QCMAENEVG--SAHAVVQLRTSRPSPPGITPRLWQDAELATGTPPVSPSKLGNPEQMLRGQPALP 452

  Fly   442 ------------------------------------------IQEPRESGG-------------- 450
                                                      :..||..|.
Human   453 RPPTSVGPASPQCPGEKGQGAPAEAPIILSSPRTSKTDSYELVWRPRHEGSGRAPILYYVVKHRK 517

  Fly   451 ------------------------------------------------------THRPKPN-QGS 460
                                                                  ..||||. ..|
Human   518 QVTNSSDDWTISGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIMAS 582

  Fly   461 RQKQMY---------------------PPTP--PNVTRLSDESVMLRWMVPRNDGLPIVIFKVQY 502
            :::|:.                     |..|  |.::..|:.||.:.|:...|.|.||..|:|:|
Human   583 KEQQIQRDDPGASPQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEY 647

  Fly   503 RMVGKRKNWQTTNDNIPYGKPKWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAK 567
            :.:.|..:|......||..:          .:..:|.|:...:|:||:.|:....:::.|..|..
Human   648 KKLKKVGDWILATSAIPPSR----------LSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRP 702

  Fly   568 FYLQ--PGAALD-PMPVPELLEIEEYSETAVVLHWSLASDADEHL-ITGYYAYYRP--SSSAGEY 626
            :.:.  .|...: |:..|.:...:..:||.::|.|.....::.:. |.|:|.||||  |.:..:|
Human   703 YVVSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDY 767

  Fly   627 FKATIEGA---HARSFKIAPLETATMYEFKLQSFSAASASEFSAL------------KQGRTQRP 676
            .|..:||.   |:    |:.|:..|.|:.|:|.|:....||||.:            :.||...|
Human   768 KKDMVEGDKYWHS----ISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKSSGQPGRLPPP 828

  Fly   677 KTSTTEEPTLQMGDRDTTTPSH-NETFNMSPMLTGTIGGGAVLILLLISTCFCVCRRRNSRSRGN 740
            ..:..:.|..:..:|...|.:. ..:.::..::.|.:.|..|||::.... ||:.|..:.:....
Human   829 TLAPPQPPLPETIERPVGTGAMVARSSDLPYLIVGVVLGSIVLIIVTFIP-FCLWRAWSKQKHTT 892

  Fly   741 NPNKPRMA---ELRDDFVPLGN-----------CSPTKQRQRTRHIHITLN--------PLAQQQ 783
            :...||.|   ......||||.           .|....|.....||:...        |..:.|
Human   893 DLGFPRSALPPSCPYTMVPLGGLPGHQASGQPYLSGISGRACANGIHMNRGCPSAAVGYPGMKPQ 957

  Fly   784 QQA---LEEKNDTDQDAPYYQRPSSYDYDP 810
            |..   |::::||  .:...|......|||
Human   958 QHCPGELQQQSDT--SSLLRQTHLGNGYDP 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ihog	NP_609085.1	IG_like	59..145	CDD:214653	24/95 (25%)
		ig	265..330	CDD:278476	23/64 (36%)
		IG_like	267..348	CDD:214653	30/82 (37%)
		Ig	314..>377	CDD:299845	24/70 (34%)
		IG_like	364..437	CDD:214653	23/72 (32%)
		IGc2	365..427	CDD:197706	20/61 (33%)
		FN3	467..565	CDD:238020	25/99 (25%)
		fn3	580..655	CDD:278470	23/80 (29%)
BOC	XP_016862930.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10874
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3750
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D102649at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.930