DRSC/TRiP Functional Genomics Resources

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Protein Alignment ihog and igdcc3

DIOPT Version :10

Sequence 1:NP_609085.1 Gene:ihog / 33972 FlyBaseID:FBgn0031872 Length:886 Species:Drosophila melanogaster
Sequence 2:XP_003199017.2 Gene:igdcc3 / 555947 ZFINID:ZDB-GENE-080303-24 Length:773 Species:Danio rerio


Alignment Length:841 Identity:185/841 - (21%)
Similarity:296/841 - (35%) Gaps:221/841 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 PESLVAPLGDEVVLECET-SLQPERFEWSHRSSRSPGA-------------------GFKYLKTG 103
            |..::|.....::|.|:. .:.|...:|     |..||                   .|:.:||.
Zfish    35 PSDIIAVQQQPLMLHCQVEGIPPISTQW-----RRSGALVQEDHNYVMFTNGSLLITHFQKIKTD 94

  Fly   104 TAKANVSQEAAISRLRVLVRPDTLGEYRCV--GWFGPLVVTSTIARLELASTSLVDAQESESPLQ 166
            .:    |.|               |:|.|:  .:||  :|.|..||::.|:.:....|    |..
Zfish    95 GS----SDE---------------GDYECIAQNFFG--LVVSRKARVQAATMADFHVQ----PES 134

  Fly   167 WRVSAGNSVLWSCGQQVQSNPSASWSYYRNG--VEIKPE--FIGTNGNLFLSNVSSESSGSYSCQ 227
            .|...|....:.|  |:...|....|:.|:|  |:...|  .:...|.|.::.|..|.||.|.|.
Zfish   135 VRADVGGVGRFQC--QIHGLPEPVISWERDGRPVDTSDERFTLLPTGVLQITGVRPEDSGVYCCV 197

  Fly   228 ATNPASGERIQLPGSLQLQVTPEQRSESKSPHLLRGQPSSQEITIREGSSLLLLCPGVGSPPPTV 292
            |.|.|.   ::.....||.|:..|.|..|.|.:|.| |.:..:|:.:  :.:|.|...|.|.|.|
Zfish   198 AHNSAG---VKHSAGAQLTVSGSQSSVYKEPMILVG-PENLTLTVHQ--TAILECVATGYPRPIV 256

  Fly   293 VWSSPD--VVGAVKNKRSKVFGHA-LEISNTRVNDAGTYICFQDN-GVRPALEHYIKVHVEQPPQ 353
            .||..|  .:|.   :..:|.|.. |.||:.||..:|.|:|..:. |.|........:.|:.|.:
Zfish   257 SWSRLDGRPIGV---EGIQVLGTGNLMISDVRVQHSGVYVCAANKPGTRVRRTAQGLLVVQAPAE 318

  Fly   354 IVRPPWADLTNEGDRLKLECKATGVPTPEIYWLLNGHSSIDDSEAELSNN--FLILHSVLKRHAG 416
            .|:||.:.....|......|.|.|.|.|:|.||.||.....|...:|.||  .|.::.|.:....
Zfish   319 FVQPPQSIARPVGTTAIFTCLAQGEPVPQITWLKNGQILEPDGHVKLRNNNSTLTIYGVTQEDEA 383

  Fly   417 YVQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPKPNQGSRQKQMYPPTPPNVTRLSDESV 481
            ..||.|.|..|...|...|.|        ..:.|.    |..         ||......||..|:
Zfish   384 IYQCIAENSAGSTQASARLTV--------LWADGL----PGM---------PTDIQADALSPTSI 427

  Fly   482 MLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPKWNSELGK-SFTASVTDLKPQHT 545
            .:.|..|..:...|:.:.:..|         .|.|.:   :.::...:.| :....:.||:|..:
Zfish   428 QVTWKEPTQNTQDIIGYVLHIR---------KTADPV---EMEYQEAVSKMTLQQVIGDLEPSTS 480

  Fly   546 YRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPELLEIEEYSETAVVLHWSLASDADEHLI 610
            |.|.:.|..|...:|.|.|:.:      :.|..:|.|..|..:..:.|.:...|..::...:.  
Zfish   481 YSFYVKAYTSRGASKASETTVE------STLGEVPAPPALFTKVINLTVIQATWEASTKMGQQ-- 537

  Fly   611 TGYYAYYR----PSSSAGEYFKATIEGAHARSFKIAPLETATMYEFKLQSFS----AASASEFSA 667
            .|:..|||    |..:....|...:     ..:.|..|:.:.:||.|:.:|:    ..:...|.:
Zfish   538 EGFNLYYRKVPVPQFTGPLTFPRDV-----MQYNITQLDPSFVYEIKILAFNQHGEGNATLRFVS 597

  Fly   668 LKQG-------------RTQRPKTSTTEEPTLQMGDRDTTTPSHNETFNMSPMLTGTIGGGAVLI 719
            ||:.             :.::.|:|||                                 |.::.
Zfish   598 LKEAVEKSVLNTPCDCVKDEQNKSSTT---------------------------------GIIIG 629

  Fly   720 LLLISTC--FCV-------------CRR-RNSRSRGNNPNKPRMAELRDD---------FVPLGN 759
            :.:..||  |||             |:. :.||..|.||....:.|....         |.|.||
Zfish   630 IHIGVTCIIFCVLFLMFSYRGRLMMCKTVQASRQAGRNPAAGVVLESSSSQGALSGPHRFSPDGN 694

  Fly   760 CSPTKQRQRTRHIHITLNPLAQQQQQALEEKNDTDQDAPYYQRPSSYDYDPTLRRMSSSSL 820
            ......:..|                      |:::....:..||.|.:.|.......|||
Zfish   695 GGAHNAKSCT----------------------DSNEMERLFSGPSHYSHPPDTTHTIESSL 733

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ihogNP_609085.1 Ig 266..348 CDD:472250 23/85 (27%)
Ig strand B 278..282 CDD:409353 1/3 (33%)
Ig strand C 291..295 CDD:409353 1/3 (33%)
Ig strand E 313..317 CDD:409353 1/4 (25%)
Ig strand F 327..332 CDD:409353 2/4 (50%)
Ig strand G 341..344 CDD:409353 0/2 (0%)
Ig 352..437 CDD:472250 27/86 (31%)
Ig strand B 369..373 CDD:409353 0/3 (0%)
Ig strand C 382..386 CDD:409353 1/3 (33%)
Ig strand E 404..407 CDD:409353 1/2 (50%)
Ig strand F 417..422 CDD:409353 2/4 (50%)
Ig strand G 430..433 CDD:409353 1/2 (50%)
FN3 467..565 CDD:238020 21/98 (21%)
FN3 582..>655 CDD:238020 15/76 (20%)
igdcc3XP_003199017.2 IgI_1_Neogenin_like 28..122 CDD:409387 23/112 (21%)
Ig strand A 28..31 CDD:409387
Ig strand A' 34..40 CDD:409387 1/4 (25%)
Ig strand B 44..54 CDD:409387 2/9 (22%)
Ig strand C 58..64 CDD:409387 1/10 (10%)
Ig strand C' 66..69 CDD:409387 2/2 (100%)
Ig strand D 74..79 CDD:409387 0/4 (0%)
Ig strand E 81..87 CDD:409387 0/5 (0%)
Ig strand F 100..107 CDD:409387 3/6 (50%)
Ig strand G 111..122 CDD:409387 5/12 (42%)
Ig 130..214 CDD:472250 25/92 (27%)
Ig strand B 143..147 CDD:409389 0/3 (0%)
Ig strand C 156..160 CDD:409389 1/3 (33%)
Ig strand E 179..183 CDD:409389 2/3 (67%)
Ig strand F 193..198 CDD:409389 2/4 (50%)
Ig strand G 207..210 CDD:409389 0/2 (0%)
Ig_3 225..297 CDD:464046 25/77 (32%)
I-set 318..404 CDD:400151 27/85 (32%)
Ig strand B 334..338 CDD:409390 0/3 (0%)
Ig strand C 347..351 CDD:409390 1/3 (33%)
Ig strand E 369..374 CDD:409390 1/4 (25%)
Ig strand F 384..389 CDD:409390 2/4 (50%)
Ig strand G 397..400 CDD:409390 1/2 (50%)
FN3 411..504 CDD:238020 23/119 (19%)
fn3 509..589 CDD:394996 17/86 (20%)
Blue background indicates that the domain is not in the aligned region.

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