DRSC/TRiP Functional Genomics Resources

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Protein Alignment ihog and Cntn1

DIOPT Version :9

Sequence 1:NP_609085.1 Gene:ihog / 33972 FlyBaseID:FBgn0031872 Length:886 Species:Drosophila melanogaster
Sequence 2:NP_001153119.1 Gene:Cntn1 / 12805 MGIID:105980 Length:1020 Species:Mus musculus


Alignment Length:1037 Identity:225/1037 - (21%)
Similarity:355/1037 - (34%) Gaps:301/1037 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MTLLTSSLLLFSLLTSRLEAI------------------PVLEKSPAHPAHSAHPAHPAHPAHPA 47
            |.||.|.|||.| |||.|...                  |:.|:.|.:..:              
Mouse     3 MPLLVSHLLLIS-LTSCLGDFTWHRRYGHGVSEEDKGFGPIFEEQPINTIY-------------- 52

  Fly    48 HPSPGVRILRAPESLVAPLGDEVVLECETSLQPERFEWSHRSSRSPGAGFKY-LKTGTAKANVSQ 111
                       ||.   .|..:|.|.|             |:..||...:|: :..|.......:
Mouse    53 -----------PEE---SLEGKVSLNC-------------RARASPFPVYKWRMNNGDVDLTNDR 90

  Fly   112 EAAISRLRVLVRPD---TLGEYRCVGWFGPLVVTSTIARLELASTSLVDAQESESPLQWRVSAGN 173
            .:.:....|:..||   ..|.|.|:......:|.||.|.|   |...:|....|...:.:|..|.
Mouse    91 YSMVGGNLVINNPDKQKDAGVYYCLASNNYGMVRSTEATL---SFGYLDPFPPEERPEVKVKEGK 152

  Fly   174 SVLWSCGQQVQSNPSASWSYYRNGVEI-----KPEFIG-TNGNLFLSNVSSESSGSYSCQATNPA 232
            .::..|..........|:.:..|...:     |..|:. |||||:::||.|...|:|||..::|:
Mouse   153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVESSDRGNYSCFVSSPS 217

  Fly   233 SGERIQLPGSLQLQVTPEQRSESKSPHLLRGQPSSQEITIR-------EGSSLLLLCPGVGSPPP 290
            ..:.: ....:.|...||:.:          :|...:|.::       .|.::.|.|..:|:|.|
Mouse   218 ITKSV-FSKFIPLIPIPERTT----------KPYPADIVVQFKDIYTMMGQNVTLECFALGNPVP 271

  Fly   291 TVVW--------SSPDVVGAVKNKRSKVFGHALEISNTRVNDAGTYICFQDNGVRPALEHYIKVH 347
            .:.|        |:.::         ...|..|:|.|.::.|.|.|.|..:| :|...:|..:::
Mouse   272 DIRWRKVLEPMPSTAEI---------STSGAVLKIFNIQLEDEGLYECEAEN-IRGKDKHQARIY 326

  Fly   348 VEQPPQIVRPPWADLTNE-----GDRLKLECKATGVPTPEIYWLLNGHSSIDDSEAELSNNFLIL 407
            |:..|:     |.:..|:     |..|...|.|||.|.|.|.||.||:|.   .:.||.     |
Mouse   327 VQAFPE-----WVEHINDTEVDIGSDLYWPCIATGKPIPTIRWLKNGYSY---HKGELR-----L 378

  Fly   408 HSVLKRHAGYVQCFARNRLGEHSAGTLLQV---------NPKQIQEPRESGG--------THRPK 455
            :.|...:||..||.|.|..|...|...|::         ||.:.:.....||        ...||
Mouse   379 YDVTFENAGMYQCIAENAYGSIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPK 443

  Fly   456 P----NQGSRQKQMYPPTPPNVTRLSDESVMLRW--------MVPRNDGLPIVIFKVQYRMVGKR 508
            |    ::|:..             |.:.|.:|.|        .:.||||.....|....|  ||.
Mouse   444 PKFSWSKGTEW-------------LVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNR--GKA 493

  Fly   509 KNWQT-------------TNDNIPYGK-----------PKWNSELGKSFTASVTDLKPQ--HTYR 547
            .:..|             .|.:|..|:           |..:.....||...|.|...:  |.:.
Mouse   494 NSTGTLVITNPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKEITHIHY 558

  Fly   548 FRILAVYSNND----NKESNTSAKFYLQPGAALD------------PMPVPELLEIEEYSETAVV 596
            .|...:.:|.:    |.:...:.::.......:|            |...|..|.||:...|:|.
Mouse   559 QRNFMLDANGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVA 623

  Fly   597 LHWSLASDADEHLITGYYAYYRPSSSAGEYFKA-----TIEGAHARSFKIAPLETATMYEFKLQS 656
            |.||..|  |.|.....|.....:..:.::..|     .||| :..|.|...|.....|||::.:
Mouse   624 LTWSRGS--DNHSPISKYTIQTKTILSDDWKDAKTDPPIIEG-NMESAKAVDLIPWMEYEFRVVA 685

  Fly   657 FSAASASEFSALKQGRTQRPKTSTTEEPTLQMGDRDTTTPSHNETFNMSPMLTGTIGGGAVLILL 721
            .:.....|.|.    .:.|.||             |...|      |::|   ..:|||......
Mouse   686 TNTLGTGEPSI----PSNRIKT-------------DGAAP------NVAP---SDVGGGGGTNRE 724

  Fly   722 LISTCFCVCRRRNSRSRGNN-----PNKPRMAELRDDFVPLGNCSPTKQRQRTRHIH----ITLN 777
            |..|...:.|..:   .|||     ..||...|   ::..:...:|    ...|::|    :|.:
Mouse   725 LTITWAPLSREYH---YGNNFGYIVAFKPFDGE---EWKKVTVTNP----DTGRYVHKDETMTPS 779

  Fly   778 PLAQQQQQALEEKND----------TDQDAPYYQRPSSYDYDPTLRRMSSSSLR-RSQRTLERAG 831
            ...|.:.:|...|.|          :.|||     ||....:..::.:|||.:. ..:..||:..
Mouse   780 TAFQVKVKAFNNKGDGPYSLVAVINSAQDA-----PSEAPTEVGVKVLSSSEISVHWKHVLEKIV 839

  Fly   832 GSNGSNNGNNNNLNQSAEAGSIENPGKPGRVLMKRPRLSSRSENL--------SSGSLNSVG 885
            .|........::...:|.           ||.:.....|:|.|||        ..|:.||.|
Mouse   840 ESYQIRYWAGHDKEAAAH-----------RVQVTSQEYSARLENLLPDTQYFIEVGACNSAG 890

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ihogNP_609085.1 IG_like 59..145 CDD:214653 19/89 (21%)
ig 265..330 CDD:278476 17/79 (22%)
IG_like 267..348 CDD:214653 20/95 (21%)
Ig 314..>377 CDD:299845 18/67 (27%)
IG_like 364..437 CDD:214653 28/77 (36%)
IGc2 365..427 CDD:197706 24/66 (36%)
FN3 467..565 CDD:238020 25/135 (19%)
fn3 580..655 CDD:278470 23/79 (29%)
Cntn1NP_001153119.1 IgI_1_Contactin-1 40..134 CDD:409436 26/137 (19%)
Ig strand B 61..65 CDD:409436 2/3 (67%)
Ig strand C 74..78 CDD:409436 1/3 (33%)
Ig strand E 96..100 CDD:409436 0/3 (0%)
Ig strand F 111..116 CDD:409436 2/4 (50%)
Ig strand G 125..128 CDD:409436 2/2 (100%)
Ig2_Contactin-2-like 142..230 CDD:409392 20/88 (23%)
Ig strand B 154..158 CDD:409392 0/3 (0%)
Ig strand C 169..173 CDD:409392 1/3 (33%)
Ig strand E 194..198 CDD:409392 3/3 (100%)
Ig strand F 208..213 CDD:409392 3/4 (75%)
Ig strand G 224..227 CDD:409392 0/2 (0%)
IgI_3_Contactin-1 241..328 CDD:143259 20/96 (21%)
Ig strand B 259..263 CDD:143259 1/3 (33%)
Ig strand C 272..276 CDD:143259 0/3 (0%)
Ig strand E 293..297 CDD:143259 1/3 (33%)
Ig strand F 307..312 CDD:143259 2/4 (50%)
Ig strand G 320..323 CDD:143259 1/2 (50%)
Ig 332..408 CDD:416386 29/88 (33%)
Ig strand A 332..335 CDD:409353 1/7 (14%)
Ig strand A' 339..343 CDD:409353 0/3 (0%)
Ig strand B 347..355 CDD:409353 2/7 (29%)
Ig strand C 361..366 CDD:409353 2/4 (50%)
Ig strand C' 368..371 CDD:409353 1/2 (50%)
Ig strand E 374..379 CDD:409353 2/9 (22%)
Ig strand F 388..395 CDD:409353 3/6 (50%)
Ig strand G 399..408 CDD:409353 2/8 (25%)
Ig5_Contactin-1 413..501 CDD:409438 21/102 (21%)
Ig strand B 432..436 CDD:409438 0/3 (0%)
Ig strand C 445..449 CDD:409438 0/3 (0%)
Ig strand E 467..471 CDD:409438 0/3 (0%)
Ig strand F 481..486 CDD:409438 0/4 (0%)
Ig strand G 494..497 CDD:409438 0/2 (0%)
Ig6_Contactin 503..603 CDD:409359 13/99 (13%)
Ig strand B 522..526 CDD:409359 0/3 (0%)
Ig strand C 537..541 CDD:409359 0/3 (0%)
Ig strand E 568..572 CDD:409359 0/3 (0%)
Ig strand F 582..587 CDD:409359 0/4 (0%)
Ig strand G 595..598 CDD:409359 0/2 (0%)
FN3 612..699 CDD:238020 24/93 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 695..719 10/49 (20%)
FN3 711..803 CDD:238020 21/104 (20%)
fn3 813..895 CDD:394996 18/89 (20%)
FN3 907..991 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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