Protein Alignment Hrb27C and NAM8

DIOPT Version :10

• Sequence 1: NP_476869.1
• Gene: Hrb27C / 33968
• FlyBaseID: FBgn0004838
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_011954.1
• Gene: NAM8 / 856486
• SGDID: S000001128
• Length: 523
• Species: Saccharomyces cerevisiae
• Alignment Length: 477
• Identity: 109/477 - (22%)
• Similarity: 148/477 - (31%)
• Gaps: 181/477 - (37%)

  Fly    14 LSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTN-VNHVLQNG------PH- 70
            :.|..|..|.||         ..:..|||:     |:.||.|...|: .|.:|:||      |:
Yeast    86 MMWNNTLNNGSR---------SSMGPKNNQ-----GYCFVDFPSSTHAANALLKNGMLIPNFPNK 136

  Fly    71 --TLDGRTIDPKPCNPRTLQKPKKGGGYKVFLGGLPSNVTETDL-RTFFNRYGKVTEVVIMYDQE 132
              .|:..|......| .:|...|.|....:|:|.|..||||:.| ..|.|||...:...|::||.
Yeast   137 KLKLNWATSSYSNSN-NSLNNVKSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQV 200

  Fly   133 KKKSRGFGFLSFEEESSVEHVTNE-RYINLNGKQVEIKKAEPRDGSGGQNSNNSTVGGAYGKLGN 196
            ...|:|:||:.|......:...:| :.:.|||:.:   |..|..|.....|.|:....:...|.|
Yeast   201 TGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAI---KVGPTSGQQQHVSGNNDYNRSSSSLNN 262

  Fly   197 ECSHWGPHHAPIN-----MMQGQ------NGQMG---------------GPPLN----------- 224
            |           |     :.:||      |..||               .|.||
Yeast   263 E-----------NVDSRFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVF 316

  Fly   225 ---------------------------MPIG-------------APNMMPGYQG----------- 238
                                       :|:|             |...:.|.||
Yeast   317 IGGLSSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLS 381

  Fly   239 WGTSPQQ----QQYGYGNSGPGSYQGWGAPPGPQGPPPQWSNYAGPQQTQGYGGYDMYNSTSTGA 299
            ||.|.:|    ||....|    |.|.....||.|.|     ||          ||  ..|::..|
Yeast   382 WGRSAKQTALLQQAMLSN----SLQVQQQQPGLQQP-----NY----------GY--IPSSTCEA 425

  Fly   300 PSGPSGGGSWNSWNMPPNSAGPTGAPGA-------------GAGTAT-DMYSRAQAWATGGPSTT 350
            |.            :|.|:...|..||.             |.|:.. ..||...|..|...|..
Yeast   426 PV------------LPDNNVSSTMLPGCQILNYSNPYANANGLGSNNFSFYSNNNATNTQATSLL 478

  Fly   351 GPVGGMPRTGP-GNSASKSGSE 371
            .....|..:|. |......|||
Yeast   479 ADTSSMDLSGTGGQQVIMQGSE 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hrb27C	NP_476869.1	RRM1_hnRNPA_hnRNPD_like	9..80	CDD:409763	20/75 (27%)
		RRM2_DAZAP1	94..173	CDD:409765	25/80 (31%)
NAM8	NP_011954.1	RRM1_NGR1_NAM8_like	55..144	CDD:410023	19/71 (27%)
		RRM2_SECp43_like	162..241	CDD:409781	26/81 (32%)
		RRM3_NGR1_NAM8_like	312..383	CDD:409782	6/70 (9%)