Protein Alignment Hrb27C and RBM38

DIOPT Version :10

• Sequence 1: NP_476869.1
• Gene: Hrb27C / 33968
• FlyBaseID: FBgn0004838
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_001278709.1
• Gene: RBM38 / 55544
• HGNCID: 15818
• Length: 271
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 66/287 - (22%)
• Similarity: 106/287 - (36%)
• Gaps: 96/287 - (33%)

  Fly    77 IDPKPCN-----PRTLQKPKKGGG-------YKVFLGGLPSNVTETDLRTFFNRYGKVTEVVIMY 129
            :.|.||.     ||.|..|....|       .|:|:||||.:.|:..||.:|..:|.:.|.|::.
Human     3 LQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVIT 67

  Fly   130 DQEKKKSRGFGF-------------LSFE-------------------EESSVEHVTNERYINLN 162
            |::..||||:||             |:|:                   :.::.|....:....::
Human    68 DRQTGKSRGYGFGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAAERACKDPNPIID 132

  Fly   163 GKQVEIK----KAEPRD-----GSGGQNSNNSTVGGAYGKLGNECSHWGPHHA-PINMMQGQNGQ 217
            |::..:.    .|:||.     ..|.|..:.:.:...||..        ||:. |..::|
Human   133 GRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGLT--------PHYIYPPAIVQ----- 184

  Fly   218 MGGPPLNMPIGAPNMMPGYQGWGTSPQQQQYGYGNSGPGSYQGWGAPPGPQGPPPQWSNY---AG 279
               |.:.:| .||  :|..    :||      |....|.|      |...|.||..:..|   |.
Human   185 ---PSVVIP-AAP--VPSL----SSP------YIEYTPAS------PAYAQYPPATYDQYPYAAS 227

  Fly   280 PQQTQGYGGYD----MYNSTSTGAPSG 302
            |.....:.||.    :..:.|..||:|
Human   228 PATAASFVGYSYPAAVPQALSAAAPAG 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hrb27C	NP_476869.1	RRM1_hnRNPA_hnRNPD_like	9..80	CDD:409763	0/2 (0%)
		RRM2_DAZAP1	94..173	CDD:409765	26/121 (21%)
RBM38	NP_001278709.1	RRM_RBM24_RBM38_like	34..141	CDD:409818	24/106 (23%)
		PABP-1234	<46..269	CDD:130689	52/244 (21%)