DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb27C and dazap1

DIOPT Version :9

Sequence 1:	NP_001162897.1	Gene:	Hrb27C / 33968	FlyBaseID:	FBgn0004838	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_012815264.1	Gene:	dazap1 / 448406	XenbaseID:	XB-GENE-856469	Length:	411	Species:	Xenopus tropicalis

Alignment Length:	442	Identity:	162/442 - (36%)
Similarity:	211/442 - (47%)	Gaps:	98/442 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DERGKLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTNVNHVLQNG 68
            ||.||||||||.|.||||.|..||.::|:::|||:||:..:.:|||||||.|.||..|..||.:.
Frog     7 DEIGKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASR 71

  Fly    69 PHTLDGRTIDPKPCNPRTLQ----KPKKG-----------GGYKVFLGGLPSNVTETDLRTFFNR 118
            |||||||.||||||.||.:|    :|::|           ...|:|:||:|.|..||:||.:|.|
Frog    72 PHTLDGRNIDPKPCTPRGMQPERTRPREGWQQKGPRTENSRSNKIFVGGIPHNCGETELREYFKR 136

  Fly   119 YGKVTEVVIMYDQEKKKSRGFGFLSFEEESSVEHVTNERYINLNGKQVEIKKAEPRDGSGGQNSN 183
            :|.|||||::||.||::.|||||::||:|.||:...|..:.::.||:||:|:|||||       :
Frog   137 FGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVNMHFHDIMGKKVEVKRAEPRD-------S 194

  Fly   184 NSTVGGAYGKLGNECSHWGPHHAPINMMQGQNGQMGGPPLNMPIGAPNMMPGYQGWGTSPQQQQY 248
            .|...|..|.     :.||..    .|....||..|.||       |.....|     |||....
Frog   195 KSQTPGPPGS-----NQWGGR----AMQSTANGWTGQPP-------PTWQQSY-----SPQGMWM 238

  Fly   249 GYGNSGPGSYQGWGAPPGPQGPPPQWSNYAGPQQTQGYGGYDMYNSTSTGAPSGPSGGGSWNSWN 313
            ..|.:...|..|:|.|.|..||||. .::|           ....||:.||...|.|
Frog   239 PTGQTIVFSTGGYGPPAGRGGPPPP-PSFA-----------PFLVSTTPGAFPPPQG-------- 283

  Fly   314 MPPNSAGPTGAPGAGAGTATDMYSRAQAWATGGPSTTGPVG----GMPRTGPGNSA---SKSGS- 370
            .||..|.|   |..|.|.........|..::|.|...|..|    ..|...||.||   ||..|
Frog   284 FPPGYATP---PPFGYGYGPPPPPPDQFVSSGVPPPPGTPGAAPLAFPPPPPGQSAQDLSKPPSG 345

  Fly   371 --EYDYGGYGSGYDYDYSNYVKQEGASNYGAGPRSAYGN---DSSTQPPYAT 417
              ::.:..:|.|.|                   .|.||.   |.:.||||.:
Frog   346 QQDFPFSQFGYGQD-------------------MSGYGQSFPDLNQQPPYTS 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb27C	NP_001162897.1	RRM1_DAZAP1	8..89	CDD:241018	50/84 (60%)
Hrb27C	NP_001162897.1	RRM2_DAZAP1	94..173	CDD:240773	39/78 (50%)
dazap1	XP_012815264.1	RRM1_DAZAP1	11..92	CDD:241018	49/80 (61%)
dazap1	XP_012815264.1	RRM2_DAZAP1	112..191	CDD:240773	39/78 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8768
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3355
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565323at2759
OrthoFinder	1	1.000	-	-		FOG0000417
OrthoInspector	1	1.000	-	-		oto102306
Panther	1	1.100	-	-	LDO	PTHR48027
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1869
SonicParanoid	1	1.000	-	-		X310
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.100