Protein Alignment Hrb27C and msi

DIOPT Version :10

• Sequence 1: NP_476869.1
• Gene: Hrb27C / 33968
• FlyBaseID: FBgn0004838
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Alignment Length: 473
• Identity: 122/473 - (25%)
• Similarity: 189/473 - (39%)
• Gaps: 123/473 - (26%)

  Fly     7 GKLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTNVNHVLQNGPHT 71
            ||||||||||:|:.:.|..||..||.:.|.::||:..:.|||||||:||.:|..|..||:...||
  Fly   203 GKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHT 267

  Fly    72 LDGRTIDPK---PCN-PRTLQKPKKGGGYKVFLGGLPSNVTETDLRTFFNRYGKVTEVVIMYDQE 132
            |||:.||||   |.| ||...|.|     |:|:||:..:.:..:::.:|:::|.|.|.|::.||:
  Fly   268 LDGKKIDPKHATPKNRPRQANKTK-----KIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQ 327

  Fly   133 KKKSRGFGFLSFEEESSVEHVTNERYINLNGKQVEIKKAEPRDG--SGGQNSNNSTVGGAYG--- 192
            .|:.|||||::||.|..|:.|....:..:..|:||.|||:|::.  ...|......:.|..|
  Fly   328 TKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTLGVQL 392

  Fly   193 --KLGNECSHWGPHHA---PINMMQGQNGQMGGP------------------------------- 221
              ..|......|...|   |:.|:|.....:..|
  Fly   393 PTAPGQLIGARGAGVATMNPLAMLQNPTQLLQSPAAAAAAQQAALISQNPFQVQNAAAAASIANQ 457

  Fly   222 ---------------------PLNMPIGAPN----MMPGYQGWGTS--------PQQQQYGYGNS 253
                                 |.::|..|..    :|..:|....:        .||||:.:...
  Fly   458 AGFGKLLTTYPQTALHSVRYAPYSIPASAATANAALMQAHQAQSVAAAAHHHQQQQQQQHHHQQQ 522

  Fly   254 GPGSYQGWGAPPGPQGPPPQWSNYAGPQQTQGYGGYDMYNSTSTGAPSGPSGGGSWNSWNMPPNS 318
            ...::..                 |..||.|.:     :|:.|..|....|...:        .:
  Fly   523 THNAHVA-----------------AAQQQQQSH-----HNAVSNPASQAHSAAAA--------AA 557

  Fly   319 AGPTGAPGAGAGTATDMYSRAQAWATGGPSTTGPVGGMP-RTGPGNSASKSGSEYDYGGYGSGYD 382
            .....|.||||..|..:.:.||        ..|.:.|.| ......:|:.:.....|..|... :
  Fly   558 LAANAANGAGAAGAHSLAAAAQ--------QAGLMAGNPLNAAAAAAAAAANPAAAYSNYALA-N 613

  Fly   383 YDYSNYVKQEGASNYGAG 400
            .|.|::...:.::.||.|
  Fly   614 VDMSSFQGVDWSTMYGMG 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hrb27C	NP_476869.1	RRM1_hnRNPA_hnRNPD_like	9..80	CDD:409763	37/70 (53%)
		RRM2_DAZAP1	94..173	CDD:409765	28/78 (36%)
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	40/73 (55%)
		RRM2_MSI	292..365	CDD:240769	25/72 (35%)