DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb27C and SPBC660.15

DIOPT Version :9

Sequence 1:	NP_001162897.1	Gene:	Hrb27C / 33968	FlyBaseID:	FBgn0004838	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_595094.1	Gene:	SPBC660.15 / 2541150	PomBaseID:	SPBC660.15	Length:	474	Species:	Schizosaccharomyces pombe

Alignment Length:	369	Identity:	126/369 - (34%)
Similarity:	181/369 - (49%)	Gaps:	70/369 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ERGKLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTNVNHVLQNGP 69
            |.||:|:|||:||||.::|..||.:||:::||.||:::.:||||||||:||.:|..||.|:.. .
pombe   161 EDGKMFIGGLNWETTDDSLRDYFEQFGEVLDCTVMRDSTTGRSRGFGFLTFKNPKCVNEVMSK-E 224

  Fly    70 HTLDGRTIDPKPCNPRTLQKPKKGGGYKVFLGGLPSNVTETDLRTFFNRYGKVTEVVIMYDQEKK 134
            |.|||:.||||...||..|:...    |:|:||:|.:.||.:.|.|||::|:|.:..:|.|::..
pombe   225 HHLDGKIIDPKRAIPREEQEKTA----KMFVGGVPGDCTEEEFRNFFNQFGRVLDATLMMDKDTG 285

  Fly   135 KSRGFGFLSFEEESSVEHVTNERYINLNGKQVEIKKAEPRDGSGGQNSNNSTVGGAYGKLGNECS 199
            :.|||||:::|.||:||...::.||.::||.||:|:|.|:  :..::|::              .
pombe   286 RPRGFGFVTYENESAVEATMSQPYITIHGKPVEVKRATPK--ASLRDSHD--------------R 334

  Fly   200 HWGPHHAPINMMQGQNGQM-GGPPLNMPIGAPNMMPGYQGWGTSPQQQQYGYG-NSGPGSYQGWG 262
            |...:|...|....||..| ||.       .|.||..|.     .|.|||... .:.|.:.   |
pombe   335 HQHGYHGNANPYYAQNMNMYGGM-------TPAMMAQYY-----RQMQQYMEAMRNMPAAA---G 384

  Fly   263 APPGPQGPPP----QWSNYAGPQQTQGYGGYD---MYNSTSTGAPSGPSGGGSWNSWNMPPNSAG 320
            |.|.||...|    .|..    ||.||...:|   |...|..|.|..||          .|:.:.
pombe   385 AVPYPQPVMPAGMADWQQ----QQQQGAAYFDPSKMNQGTGDGVPFSPS----------MPSGSS 435

  Fly   321 PTGAPGAGAGTATDMYSRAQAWATGGPSTTGPVGGMPRTGPGNS 364
            ..|..|...|.......|.:....||           .||.|:|
pombe   436 RGGYHGRNPGGPNRQRYRGRRDGRGG-----------NTGGGHS 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb27C	NP_001162897.1	RRM1_DAZAP1	8..89	CDD:241018	42/80 (53%)
Hrb27C	NP_001162897.1	RRM2_DAZAP1	94..173	CDD:240773	33/78 (42%)
SPBC660.15	NP_595094.1	RRM1_Hrp1p	165..240	CDD:241021	39/75 (52%)
SPBC660.15	NP_595094.1	RRM2_Hrp1p	248..322	CDD:240776	32/73 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	77	1.000	Domainoid score	I2414
eggNOG	1	0.900	-	-		E1_KOG4205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I1134
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000417
OrthoInspector	1	1.000	-	-		oto100469
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR48027
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1869
SonicParanoid	1	1.000	-	-		X310
TreeFam	1	0.960	-	-
	10	9.950