Protein Alignment Hrb27C and Ncl

DIOPT Version :10

• Sequence 1: NP_476869.1
• Gene: Hrb27C / 33968
• FlyBaseID: FBgn0004838
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_036881.2
• Gene: Ncl / 25135
• RGDID: 3153
• Length: 714
• Species: Rattus norvegicus
• Alignment Length: 268
• Identity: 66/268 - (24%)
• Similarity: 103/268 - (38%)
• Gaps: 59/268 - (22%)

  Fly     5 ERGKLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTNVNHVLQN-G 68
            |...|.:..||:..|:|.|...|    :....:.:..|..|:|:|:.|:.||...:....|.: .
  Rat   488 ESKTLVLSNLSYSATEETLQEVF----EKATFIKVPQNPHGKSKGYAFIEFASFEDAKEALNSCN 548

  Fly    69 PHTLDGRTIDPKPCNPRTLQKPKKGGGYKVFLGGLPSNVTETDLRTFFNRYGKVTEVVIMYDQEK 133
            ...::||||..:...||.....:......:|:.||..:.||..|:..|.  |.| ...|:.|:|.
  Rat   549 KMEIEGRTIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFE--GSV-RARIVTDRET 610

  Fly   134 KKSRGFGFLSF--EEESSVEHVTNERYINLNGKQVEIKKAEPRDGSGGQNSNNSTVGGAYGKLGN 196
            ..|:||||:.|  ||::.......|.. .::|.:|.:..|:|: |.||....    ||..|..|
  Rat   611 GSSKGFGFVDFNSEEDAKAAKEAMEDG-EIDGNKVTLDWAKPK-GEGGFGGR----GGGRGGFG- 668

  Fly   197 ECSHWGPHHAPINMMQGQNGQMGGPPLNMPIGAPNMMPGYQGWGTSPQQQQYGYGNSGPGSYQGW 261
                            |:.|..||                          :.|:|..|.|.:.|.
  Rat   669 ----------------GRGGGRGG--------------------------RGGFGGRGRGGFGGR 691

  Fly   262 GAPPGPQG 269
            |...|.:|
  Rat   692 GGFRGGRG 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hrb27C	NP_476869.1	RRM1_hnRNPA_hnRNPD_like	9..80	CDD:409763	19/71 (27%)
		RRM2_DAZAP1	94..173	CDD:409765	24/80 (30%)
Ncl	NP_036881.2	8 X 8 AA tandem repeats of X-T-P-X-K-K-X-X	58..135
		RRM1_NCL	312..386	CDD:409837
		RRM2_NCL	395..470	CDD:409838
		RRM3_NCL	489..561	CDD:409839	19/75 (25%)
		RRM4_NCL	576..653	CDD:409840	25/81 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	646..714		21/102 (21%)