DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb27C and rsp-1

DIOPT Version :9

Sequence 1:	NP_001162897.1	Gene:	Hrb27C / 33968	FlyBaseID:	FBgn0004838	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_496442.1	Gene:	rsp-1 / 174748	WormBaseID:	WBGene00004698	Length:	312	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	44/193 - (22%)
Similarity:	72/193 - (37%)	Gaps:	73/193 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 KVFLGGLPSNVTETDLRTFFNRYGKVTEVVIMYDQEKKKSRGFGFLSFEEESSVEHVTNERYINL 161
            ::::|.|.|.|:|.|:..||..||::.:|::        ..||||:.|:::...|...::    |
Worm     4 RIYIGRLTSRVSEKDIEHFFRGYGQIRDVLL--------KNGFGFVEFDDKRDAEDAVHD----L 56

  Fly   162 NGKQ-----VEIKKAEPRDGSGGQNSNNSTVGGAYGKLGNECSHWGPHHAPINMMQGQNGQMGGP 221
            |||:     |.:..::||.|.|.:        |.:|                      .|..||.
Worm    57 NGKELGGERVILDYSKPRGGGGDR--------GGFG----------------------GGGRGGA 91

  Fly   222 PLNMPIGAPNMMPGYQGWGTSPQQQQYGYGNSGPGSYQGWGAPPGPQGPPPQWSNYAGPQQTQ 284
            .::          .|.|.|        |.|......|.        :|||.:.|.|..|..|:
Worm    92 RVS----------SYSGGG--------GGGRDRFDRYD--------RGPPRRESRYGRPYSTR 128

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb27C	NP_001162897.1	RRM1_DAZAP1	8..89	CDD:241018
Hrb27C	NP_001162897.1	RRM2_DAZAP1	94..173	CDD:240773	22/80 (28%)
rsp-1	NP_496442.1	RRM	<3..180	CDD:223796	44/193 (23%)
		RRM1_SRSF4_like	4..73	CDD:240783	22/80 (28%)
		RRM2_SRSF4_like	129..200	CDD:241044	44/193 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910