Protein Alignment Hrb27C and MSI2

DIOPT Version :9

• Sequence 1: NP_001162897.1
• Gene: Hrb27C / 33968
• FlyBaseID: FBgn0004838
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: XP_005257071.1
• Gene: MSI2 / 124540
• HGNCID: 18585
• Length: 346
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 127/395 - (32%)
• Similarity: 182/395 - (46%)
• Gaps: 97/395 - (24%)

  Fly     3 EDERGKLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTNVNHVLQN 67
            :.:.||:|:|||||:|:.::|..||.:||:|.:|:||::..:.|||||||||||||.:|:.||..
Human    17 QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81

  Fly    68 GPHTLDGRTIDPKPCNPRTLQKPKKGGGYKVFLGGLPSNVTETDLRTFFNRYGKVTEVVIMYDQE 132
            ..|.||.:|||||...||..|........|:|:|||.:|....|::.:|.::|||.:.::|:|:.
Human    82 PHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKT 146

  Fly   133 KKKSRGFGFLSFEEESSVEHVTNERYINLNGKQVEIKKAEPRDGSGGQNSNNSTVGGAYGKLGNE 197
            ..:.|||||::||.|..||.|....:..:|.|.||.|||:|::
Human   147 TNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKE---------------------- 189

  Fly   198 CSHWGPHHAPINMMQGQNGQMGGPPLNMP--------IGAPNMMP----GYQGWGTSPQQQQYGY 250
                      :....|..|:..|.|..|.        :|.||.:.    ||.|:..|       |
Human   190 ----------VMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPS-------Y 237

  Fly   251 GNSGPGSYQGWGAPPGPQGPPPQWSNYAGPQQTQGYGGYDMYNSTST----GAPSGPSGGGSWNS 311
            |      ||..|.|....||...    |.....:|    .:.||.|.    |||:.|:|.
Human   238 G------YQFPGFPAAAYGPVAA----AAVAAARG----SVLNSYSAQPNFGAPASPAGS----- 283

  Fly   312 WNMPPNSAGPTGAPGAGA-GTATDMYSRAQAWATGGPSTTGPVGGMPRTGPGNSASKSGSEYDYG 375
                 |.|.|.|.|||.: |...|:|         ||::..       :|.||..| :.|.....
Human   284 -----NPARPGGFPGANSPGPVADLY---------GPASQD-------SGVGNYIS-AASPQPGS 326

  Fly   376 GYGSG 380
            |:|.|
Human   327 GFGHG 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hrb27C	NP_001162897.1	RRM1_DAZAP1	8..89	CDD:241018	43/80 (54%)
		RRM2_DAZAP1	94..173	CDD:240773	31/78 (40%)
MSI2	XP_005257071.1	RRM1_MSI2	17..109	CDD:410153	45/91 (49%)
		PABP-1234	<35..343	CDD:130689	118/377 (31%)
		RRM2_MSI	111..184	CDD:240769	28/72 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565323at2759
OrthoFinder	1	1.000	-	-		FOG0000417
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1869
SonicParanoid	1	1.000	-	-		X310
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850