DRSC/TRiP Functional Genomics Resources

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Protein Alignment x16 and NPL3

DIOPT Version :10

Sequence 1:NP_723226.1 Gene:x16 / 33967 FlyBaseID:FBgn0028554 Length:258 Species:Drosophila melanogaster
Sequence 2:NP_010720.3 Gene:NPL3 / 852042 SGDID:S000002840 Length:414 Species:Saccharomyces cerevisiae


Alignment Length:335 Identity:71/335 - (21%)
Similarity:98/335 - (29%) Gaps:152/335 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 SDRKVYVGDLGNNARKNDLEYVFGAYGSLRSVWIARNPPGFAFVEFESARDAADAVRGLDGRTVC 70
            |:.:::|.....:.::::|..:||.:|.::.|.|..   ||||||||.|..||.|:..:.|::..
Yeast   123 SNTRLFVRPFPLDVQESELNEIFGPFGPMKEVKILN---GFAFVEFEEAESAAKAIEEVHGKSFA 184

  Fly    71 ------------GRRARVELST------------------------------------------- 80
                        .:|.|:.:..                                           
Yeast   185 NQPLEVVYSKLPAKRYRITMKNLPEGCSWQDLKDLARENSLETTFSSVNTRDFDGTGALEFPSEE 249

  Fly    81 -----------------------------------------------------GKYARSGGGGGG 92
                                                                 |.::|.|.||..
Yeast   250 ILVEALERLNNIEFRGSVITVERDDNPPPIRRSNRGGFRGRGGFRGGFRGGFRGGFSRGGFGGPR 314

  Fly    93 GGGGGGGGGLGGRDRGG-GGRGDDKCYECGGRGHFARHCRERKARQRRRSNSFSRSRSTSRRRRT 156
            ||.||..||.||..||| ||      |..||.|.                   ||....|.|...
Yeast   315 GGFGGPRGGYGGYSRGGYGG------YSRGGYGG-------------------SRGGYDSPRGGY 354

  Fly   157 RSKSGTRSRSRSAGSVGRRSGRSNGRDENGSASRYSDHERNGSGAVDSPPPPKRRYEDEDDDRVR 221
            .|..|..||   .|..|.|:.....|...|.:....|..|...|      ||:..|      |.|
Yeast   355 DSPRGGYSR---GGYGGPRNDYGPPRGSYGGSRGGYDGPRGDYG------PPRDAY------RTR 404

  Fly   222 GSPRSRSRSR 231
            .:||.||.:|
Yeast   405 DAPRERSPTR 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
x16NP_723226.1 RRM_SRSF3_like 9..81 CDD:409808 22/179 (12%)
NPL3NP_010720.3 PHA03247 <11..87 CDD:223021
RBD_RRM1_NPL3 126..192 CDD:409777 20/68 (29%)
RRM2_SRSF1_4_like 200..271 CDD:409776 1/70 (1%)
Blue background indicates that the domain is not in the aligned region.

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