Protein Alignment x16 and SRSF6

DIOPT Version :10

• Sequence 1: NP_723226.1
• Gene: x16 / 33967
• FlyBaseID: FBgn0028554
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_006266.2
• Gene: SRSF6 / 6431
• HGNCID: 10788
• Length: 344
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 106/351 - (30%)
• Similarity: 139/351 - (39%)
• Gaps: 110/351 - (31%)

  Fly     9 KVYVGDLGNNARKNDLEYVFGAYGSLRSVWIARNPPGFAFVEFESARDAADAVRGLDGRTVCGRR 73
            :||:|.|..|.|:.|::..|..||.|..|.:..   |:.|||||.:|||.|||..|:|:.:||.|
Human     3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKN---GYGFVEFEDSRDADDAVYELNGKELCGER 64

  Fly    74 ARVELSTGKYARSGG---GGGGGGGGGGGGGLGGRDRGG-------------------------- 109
            ..||.:.|......|   |...||||.......|||:.|
Human    65 VIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDF 129

  Fly   110 ---GG--------------------------RGDDKC--YECGGR------------------GH 125
               .|                          |..||.  .|..||                  |.
Human   130 MRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGS 194

  Fly   126 FARHCRERKARQRRRSNSFSRSRSTSR-RRRTRSKSGTRSRSRSAGSVGRRSGRSNGRDENG--- 186
            .:|....|::|.|.|.:|.|||||.|: |.|:||:|..||||||.|...|...:|..:.:.|
Human   195 RSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHS 259

  Fly   187 -SASRYSD-HERNGSGAVDSPPPPKRRYEDEDDDRVRGSPRSRSRSRSASP------AVRRGSPP 243
             |.||..| :|::.|.:....|      ::.....::...||||:|||.||      ..|..|||
Human   260 HSRSRSKDEYEKSRSRSRSRSP------KENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPP 318

  Fly   244 RRRGDS-----------SASRSVSRD 258
            .:|..|           |.|||.|||
Human   319 PKRATSRSRSRSRSKSRSRSRSSSRD 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
x16	NP_723226.1	RRM_SRSF3_like	9..81	CDD:409808	31/71 (44%)
SRSF6	NP_006266.2	RRM1_SRSF6	1..72	CDD:410009	31/71 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..103		9/27 (33%)
		RRM2_SRSF6	110..182	CDD:410159	7/71 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..344		55/173 (32%)