Protein Alignment x16 and SRSF4

DIOPT Version :10

• Sequence 1: NP_723226.1
• Gene: x16 / 33967
• FlyBaseID: FBgn0028554
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_005617.2
• Gene: SRSF4 / 6429
• HGNCID: 10786
• Length: 494
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 105/379 - (27%)
• Similarity: 136/379 - (35%)
• Gaps: 140/379 - (36%)

  Fly     9 KVYVGDLGNNARKNDLEYVFGAYGSLRSVWIARNPPGFAFVEFESARDAADAVRGLDGRTVCGRR 73
            :||:|.|...||:.|:|..|..||.:..|.:..   |:.||||:..|||.|||..|:|:.:||.|
Human     3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKN---GYGFVEFDDLRDADDAVYELNGKDLCGER 64

  Fly    74 ARVELSTGKYARSGGGGGGGGGGGGGGGL--GGRDRGG--------------------------- 109
            ..||     :||.....|..|.|..|.|.  .|||:.|
Human    65 VIVE-----HARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYM 124

  Fly   110 ------------GGRGDDKCYE---------------------------------------CGGR 123
                        .||.::...|                                       ...|
Human   125 RQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSR 189

  Fly   124 GHF-----ARHCRERKAR----------QRRRSNSFSRSRSTSRRR------------RTRSKSG 161
            .|.     :||.|:.::|          .|.||.|.|||||.||.|            |:.||..
Human   190 SHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEK 254

  Fly   162 TRSRSRSAG------------------SVGRRSGRSNGRDENGSASRYSDHER----NGSGAVD- 203
            :||||.|||                  :||:...||..|.::.|.||....||    ...|:|.
Human   255 SRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSR 319

  Fly   204 SPPPPKRRYEDEDDDRVRGSPRSRSRSRSASPAVRRGSPPRRRGDSSASRSVSR 257
            .....|...:.....|.:|..||||||||.|...|:|.  :|..:.|.|||.||
Human   320 GRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGR--KRSREESRSRSRSR 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
x16	NP_723226.1	RRM_SRSF3_like	9..81	CDD:409808	30/71 (42%)
SRSF4	NP_005617.2	RRM1_SRSF4	1..87	CDD:410007	36/91 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	72..95		7/22 (32%)
		RRM2_SRSF4_like	104..175	CDD:410012	3/70 (4%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..494		61/205 (30%)