DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment x16 and RBM4

DIOPT Version :9

Sequence 1:	NP_723226.1	Gene:	x16 / 33967	FlyBaseID:	FBgn0028554	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_002887.2	Gene:	RBM4 / 5936	HGNCID:	9901	Length:	364	Species:	Homo sapiens

Alignment Length:	201	Identity:	50/201 - (24%)
Similarity:	85/201 - (42%)	Gaps:	31/201 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SRHPSDRKVYVGDLGNNARKNDLEYVFGAYGSLRSVWIARNPPGFAFVEFESARDAADAVRGLDG 66
            ::..:..|::||::.......:|...|..||.:....|.::   :|||..|.|.||.:|:||||.
Human    72 NKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKD---YAFVHMERAEDAVEAIRGLDN 133

  Fly    67 RTVCGRRARVELSTGKYARSGGGGGGGGGGGGGGGLGGRDRGGGGRGDDKCYECGGRGHFARHCR 131
            ....|:|..|:|||.:...:.|.|               |:.|       ||.||..||:::.|.
Human   134 TEFQGKRMHVQLSTSRLRTAPGMG---------------DQSG-------CYRCGKEGHWSKECP 176

  Fly   132 -ERKARQRRRSNSFSRSRSTSRRRRTRSKSGTRSRSRSAGSVGR-----RSGRSNGRDENGSASR 190
             :|..|....:..::......|...|.|...:...:.:.|::..     |:.||.......:||.
Human   177 IDRSGRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGALDAYYKRCRAARSYEAVAAAAASV 241

  Fly   191 YSDHER 196
            |:..|:
Human   242 YNYAEQ 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
x16	NP_723226.1	RRM	<1..>82	CDD:223796	26/79 (33%)
x16	NP_723226.1	RRM_SRSF3_like	9..81	CDD:240819	25/71 (35%)
RBM4	NP_002887.2	RRM1_RBM4	2..68	CDD:410018
		RRM2_RBM4	78..144	CDD:410019	22/68 (32%)
		PTZ00368	<145..>181	CDD:173561	15/57 (26%)
		ZnF_C2HC	161..176	CDD:197667	7/21 (33%)
		Interaction with TNPO3. /evidence=ECO:0000269\|PubMed:12628928	196..364		11/52 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910