DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment x16 and rbm4.2

DIOPT Version :9

Sequence 1:	NP_723226.1	Gene:	x16 / 33967	FlyBaseID:	FBgn0028554	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_955971.1	Gene:	rbm4.2 / 557528	ZFINID:	ZDB-GENE-030131-3019	Length:	385	Species:	Danio rerio

Alignment Length:	302	Identity:	68/302 - (22%)
Similarity:	103/302 - (34%)	Gaps:	78/302 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KVYVGDLGNNARKNDLEYVFGAYGSLRSVWIARNPPGFAFVEFESARDAADAVRGLDGRTVCGRR 73
            |::|.::.:.....:|...|..||.:....|.::   :|||..|...||.:|:.||:..|..|:.
Zfish    79 KLHVSNISSGCTNQELRAKFEEYGPVVECDIVKD---YAFVHMERMDDAMEAISGLENTTFQGKL 140

  Fly    74 ARVELSTGKYARSGGGGGGGGGGGGGGGLGGRDRGGGGRGDDKCYECGGRGHFARHCRERKARQR 138
            .:|:|||.:...:.|.|               |:.|       ||.||.:||:::.||..:....
Zfish   141 IKVQLSTSRLRTAPGMG---------------DQTG-------CYICGEQGHWSKDCRHSQNGSY 183

  Fly   139 RRSNSFSRSRSTSRRRRTRSKSG------------------TRSRSRSAGSVGRR-SGRSNGRDE 184
            ........||...|...:....|                  ..||..|.|..|.. ..|...|..
Zfish   184 GGGMGGYPSRGPPRGGPSYGMGGPGGHPSRGYPAGPLPPPPPMSRRPSYGEYGAEPRERYLTRVP 248

  Fly   185 NGSASRYSDHERNGSGAVD----------------------SPPPPKRRYEDEDDDRVRGSPRSR 227
            .|...|...:||:..|::|                      .||||..........|:|.:|.|.
Zfish   249 TGYPERPPVYERDRFGSIDYYEKFRAHPAASSYYEDRPHAIPPPPPPPPLSSSSLSRMRLAPPSL 313

  Fly   228 S------------RSRSASPAVRRGSPPRRRGDSSASRSVSR 257
            .            .:.:|:...|..||.||.|..:...|..|
Zfish   314 DPYERRPLAPPPPTAAAAASFARDRSPIRRVGAGAEGYSYER 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
x16	NP_723226.1	RRM	<1..>82	CDD:223796	22/72 (31%)
x16	NP_723226.1	RRM_SRSF3_like	9..81	CDD:240819	21/71 (30%)
rbm4.2	NP_955971.1	RRM1_2_CoAA_like	3..68	CDD:240789
		RRM_SF	78..144	CDD:302621	18/67 (27%)
		ZnF_C2HC	161..177	CDD:197667	8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910