Protein Alignment x16 and HNRNPC

DIOPT Version :9

• Sequence 1: NP_723226.1
• Gene: x16 / 33967
• FlyBaseID: FBgn0028554
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_001070910.1
• Gene: HNRNPC / 3183
• HGNCID: 5035
• Length: 306
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 62/249 - (24%)
• Similarity: 97/249 - (38%)
• Gaps: 39/249 - (15%)

  Fly     9 KVYVGDLGN-NARKNDLEYVFGAYGSLRSVWIARNPPGFAFVEFESARDAADAVRGLDGRTVCGR 72
            :|::|:|.. ..:|:|:|.:|..||.:....:.:   |||||::.:.|:|..||.|.|||.:.|:
Human    17 RVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHK---GFAFVQYVNERNARAAVAGEDGRMIAGQ 78

  Fly    73 RARVELSTGKYARSGGGGGGGGGGGGGGGL-----------GGRDRGGGGRGD--DKCYECGGR- 123
            ...:.|:.......|..|.........|.:           ...|.....:.|  |:.|....|
Human    79 VLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARV 143

  Fly   124 ---GHFARHCRERKARQRRRSNSFSRSRSTSRRRRTRSKSGTRSRSRSAGSVGRRSGRSNGRDEN 185
               ...||.....| |||...|       |||    |.|||..|:|...||  .:||:..|.|..
Human   144 PPPPPIARAVVPSK-RQRVSGN-------TSR----RGKSGFNSKSGQRGS--SKSGKLKGDDLQ 194

  Fly   186 GSASRYSDHERNGSGAVDSPPPPKRRYEDEDDDRVRGSPRSRSRSRSASPAVRR 239
            ......:..::.    |||......:.|.|...:.......:|....:|.:|::
Human   195 AIKKELTQIKQK----VDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVKK 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
x16	NP_723226.1	RRM	<1..>82	CDD:223796	24/73 (33%)
		RRM_SRSF3_like	9..81	CDD:240819	24/72 (33%)
HNRNPC	NP_001070910.1	RRM_hnRNPC	10..93	CDD:410015	24/78 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..190		21/64 (33%)
		Nuclear localization signal. /evidence=ECO:0000255	155..161		3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..306		3/24 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S3571
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950