DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nop5 and NOP56

DIOPT Version :9

Sequence 1:	NP_477412.1	Gene:	nop5 / 33966	FlyBaseID:	FBgn0026196	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_176007.1	Gene:	NOP56 / 842063	AraportID:	AT1G56110	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	216/548 - (39%)
Similarity:	313/548 - (57%)	Gaps:	65/548 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFVLYETPAGYAIFKL--LDE--KKLEQVDNLYQEFETPEKANKLLKLKHFEKFNDTTEALAAAT 61
            |:|:||:.:||.:|::  |||  :..|.|.....:.   .:..::::|..|..|....:||....
plant     3 MYVIYESSSGYGLFEVHGLDEIGQNTEAVRTSVSDL---SRFGRVVQLTAFHPFESALDALNQVN 64

  Fly    62 AAVEGKVAKPLKKTLKKLLVDDVQS------SLLVADAKLGTAIKDKLSVQCVCNTGVQELMRCI 120
            |..||.:...|:..| :|.:..|:.      ||.:|:.|||:.|.:...:.|..|..|.||:|.:
plant    65 AVSEGVMTDELRSFL-ELNLPKVKEGKKPKFSLGLAEPKLGSHIFEATKIPCQSNEFVLELLRGV 128

  Fly   121 RQQADSLLGGLPKREMTAMALGLAHSLSRYKLKFSPDKIDTMIVQAQCLLDDLDKELNNYMMRAR 185
            ||..|..:..|...::....||||||.||.|:||:.:::|.|::||..:||.|||::|::.||.|
plant   129 RQHFDRFIKDLKPGDLEKSQLGLAHSYSRAKVKFNVNRVDNMVIQAIFMLDTLDKDINSFAMRVR 193

  Fly   186 EWYGWHFPELGKIITDNIAFVKTIKLVGTRDNMATSD----LSDIL-PEDVEEKVKEAAEISMGT 245
            |||.||||||.||:.||..:.:..|::..:..: |.|    |:::| .||..::|.||.:.|||:
plant   194 EWYSWHFPELVKIVNDNYLYARVSKMIDDKSKL-TEDHIPMLTEVLGDEDKAKEVIEAGKASMGS 257

  Fly   246 EISEEDVLNIQCLCDEIISINDYRTHLYDYLKARMMAMAPNLTVLVGDTVGARLIAHAGSLINLA 310
            ::|..|::|:|....:::.:.|||..|||||..:|..:||||..|:|:.||||||:|||||.|||
plant   258 DLSPLDLINVQTFAQKVMDLADYRKKLYDYLVTKMSDIAPNLAALIGEMVGARLISHAGSLTNLA 322

  Fly   311 KHPSSTVQILGAEKALFRALKTKKDTPKYGLIYHAQLVGQASQKNKGKMSRSLAAKASLATRVDA 375
            |.||||:|||||||||||||||:.:|||||||:|:..:|:||.||||:::|.||.|.|:|:|:|.
plant   323 KCPSSTLQILGAEKALFRALKTRGNTPKYGLIFHSSFIGRASAKNKGRIARYLANKCSIASRIDC 387

  Fly   376 FGEEATFELGAAHKVKLESRLRLLEEG---------------NLRKLSGTGK-------AKAKFE 418
            |.:.||...|...:.::|.||...::|               || |....||       .|:|.:
plant   388 FADGATTAFGEKLREQVEERLEFYDKGVAPRKNVDVMKEVIENL-KQEEEGKEPVDASVKKSKKK 451

  Fly   419 KYQAKSEVFTYQPEADNTLNVKKKRKHSESEQQTPVKKEEPAEEEAEVKSEKKKKKKKKQKDEEV 483
            |.:.:.|......|.|.:...|||.|          :|.|.|||..  ||||||.||.|...||
plant   452 KAKGEEEEEVVAMEEDKSEKKKKKEK----------RKMETAEENE--KSEKKKTKKSKAGGEE- 503

  Fly   484 EAVEEAAAPEPEDQPTPAKKKKKSKHQE 511
                     |.:|..:..|||||||..|
plant   504 ---------ETDDGHSTKKKKKKSKSAE 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nop5	NP_477412.1	NOP5NT	2..>52	CDD:285382	14/53 (26%)
		NOSIC	163..214	CDD:197999	25/50 (50%)
		Nop	169..397	CDD:280047	117/232 (50%)
NOP56	NP_176007.1	NOP5NT	4..69	CDD:400464	17/67 (25%)
NOP56	NP_176007.1	SIK1	46..414	CDD:224415	162/369 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1498
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D632707at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820