DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nop5 and AT5G27140

DIOPT Version :9

Sequence 1:	NP_477412.1	Gene:	nop5 / 33966	FlyBaseID:	FBgn0026196	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001330282.1	Gene:	AT5G27140 / 832772	AraportID:	AT5G27140	Length:	450	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	223/507 - (43%)
Similarity:	300/507 - (59%)	Gaps:	84/507 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFVLYETPAGYAIFKLLDEKKLEQVDNLYQEFETPEKANKLLKLKHFEKFN-DTTEALAAATAAV 64
            |.||:||..|:|:||:|||.||..|::|..||.:.|.|.: :.|..|.|.| |..|.||
plant     1 MLVLFETSGGFALFKVLDEGKLSNVEDLGTEFYSAESARR-MGLHKFLKNNCDDGEILA------ 58

  Fly    65 EGKVAKPLKKTLKKLLVDDVQSSLLVADAKLGTAIKDKLSVQCVCNTGVQELMRCIRQQADSLLG 129
                                     |||.|||..|.:||.::||.|..|.||:|.:|.|...||.
plant    59 -------------------------VADPKLGDIITEKLDIECVHNDAVMELLRGVRSQLTELLS 98

  Fly   130 GLPKREMTAMALGLAHSLSRYKLKFSPDKIDTMIVQAQCLLDDLDKELNNYMMRAREWYGWHFPE 194
            ||...::..::|.|:|.|:|||||.:.||::|||:.:..||||||||||.|.....|.||.||||
plant    99 GLDDNDLAPVSLELSHILARYKLKITSDKVETMIILSISLLDDLDKELNTYTTSVCELYGLHFPE 163

  Fly   195 LGKIITDNIAFVKTIKLVGTRDNMATSDLSDILPEDVEEKVKEAAEISMGTEISEEDVLNIQCLC 259
            |..|:.|||.:.|.:||:|.|.|.||.|.|:||.::||.::|||:.:|..||:|:.|:::||.||
plant   164 LANIVQDNILYAKVVKLMGNRINAATLDFSEILADEVEAELKEASMVSTRTEVSDLDLMHIQELC 228

  Fly   260 DEIISINDYRTHLYDYLKARMMAMAPNLTVLVGDTVGARLIAHAGSLINLAKHPSSTVQILGAEK 324
            |:::||.:.:|.|.|.||.:|..:|||||.|||:.||||||:|.|||.||:|.|.||:|||||||
plant   229 DQVLSIAEDKTLLCDDLKNKMNKIAPNLTALVGELVGARLISHCGSLWNLSKLPWSTIQILGAEK 293

  Fly   325 ALFRALKTKKDTPKYGLIYHAQLVGQASQKNKGKMSRSLAAKASLATRVDAFGEEATFELGAAHK 389
            .|::|||||:.||||||||||.||.||:.:||||::||||||::||.|.||||......:|...:
plant   294 TLYKALKTKQATPKYGLIYHAPLVRQAAPENKGKIARSLAAKSALAIRCDAFGNGQDNTMGVESR 358

  Fly   390 VKLESRLRLLEEGNLRKLSGTGKAKAKFEKYQAKSEVFTYQPEADNTLNVKKKRKHSESEQQTPV 454
            :|||:|||.||.|:|...                        |.:..:|.|..:|.::.|
plant   359 LKLEARLRNLEGGDLGAC------------------------EEEEEVNDKDTKKEADDE----- 394

  Fly   455 KKEEPAEEEAEVKSEKKKKKKKKQKDEEVEAVEEAAAPEPEDQPTPAKKKKK 506
              |||..||.         .||::|:.|:|.||:           ||||.|:
plant   395 --EEPKTEEC---------SKKRKKEAELETVED-----------PAKKSKQ 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nop5	NP_477412.1	NOP5NT	2..>52	CDD:285382	23/50 (46%)
		NOSIC	163..214	CDD:197999	27/50 (54%)
		Nop	169..397	CDD:280047	131/227 (58%)
AT5G27140	NP_001330282.1	NOP5NT	2..>48	CDD:285382	21/46 (46%)
		NOSIC	132..183	CDD:197999	27/50 (54%)
		Nop	138..366	CDD:280047	131/227 (58%)
		RNA_polI_A34	<377..425	CDD:285426	22/75 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	305	1.000	Domainoid score	I326
eggNOG	1	0.900	-	-		E1_COG1498
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54819
OrthoDB	1	1.010	-	-		D632707at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2635
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10894
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2530
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.890