Protein Alignment nop5 and NOP56

DIOPT Version :10

• Sequence 1: NP_477412.1
• Gene: nop5 / 33966
• FlyBaseID: FBgn0026196
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_006383.2
• Gene: NOP56 / 10528
• HGNCID: 15911
• Length: 594
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 209/537 - (38%)
• Similarity: 307/537 - (57%)
• Gaps: 50/537 - (9%)

  Fly     1 MFVLYETPAGYAIFKLLDEKKLEQVDNLYQEFETP----EKANKLLKLKHFEKFNDTTEALAAAT 61
            :.||:|...|||:..|   |::|::..|..:.|..    .|.:.:::|..|..|..:..||..|.
Human     4 LHVLFEHAVGYALLAL---KEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENAN 65

  Fly    62 AAVEGKVAKPLKKTLKKLLVDDVQSSLL-VADAKLGTAIKDKLSVQCVCNTGVQELMRCIRQQAD 125
            |..||.|.:.|:..|:..|....:..|| |.|.|:|.||:::|...|.....:.|::|.:|....
Human    66 AVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFH 130

  Fly   126 SLLGGLPKREMTAMALGLAHSLSRYKLKFSPDKIDTMIVQAQCLLDDLDKELNNYMMRAREWYGW 190
            :|:.||.........|||.||.||.|:||:.:::|.||:|:..|||.|||::|.:.||.|||||:
Human   131 NLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGY 195

  Fly   191 HFPELGKIITDNIAFVKTIKLVGTRDNMATSDLSDILPEDVEEKVKE-------------AAEIS 242
            |||||.|||.||..:.:..:.:|.|..         |.||..||::|             |:..|
Human   196 HFPELVKIINDNATYCRLAQFIGNRRE---------LNEDKLEKLEELTMDGAKAKAILDASRSS 251

  Fly   243 MGTEISEEDVLNIQCLCDEIISINDYRTHLYDYLKARMMAMAPNLTVLVGDTVGARLIAHAGSLI 307
            ||.:||..|::||:.....::|:::||..|:.||:::|..:||:|:.|:|:.||||||||||||.
Human   252 MGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLT 316

  Fly   308 NLAKHPSSTVQILGAEKALFRALKTKKDTPKYGLIYHAQLVGQASQKNKGKMSRSLAAKASLATR 372
            ||||:|:||||||||||||||||||:.:|||||||:|:..:|:|:.||||::||.||.|.|:|:|
Human   317 NLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASR 381

  Fly   373 VDAFGEEATFELGAAHKVKLESRLRLLEEGNLRKLSGTGKAKAKFEKYQAKSEVFTYQPEADNTL 437
            :|.|.|..|...|...:.::|.||...|.|.:.:.:.....:|..:..:|.:|: |.:.|.....
Human   382 IDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEI-TRKLEKQEKK 445

  Fly   438 NVKKKRKH--------SESEQQTPVKKEEPAEEEAEVKSEKKKKKKKKQKDEEVEAVEEAAAPEP 494
            .:||::|.        ||:...||        ||.|..|| |.|||||||.:||.  :|....:|
Human   446 RLKKEKKRLAALALASSENSSSTP--------EECEEMSE-KPKKKKKQKPQEVP--QENGMEDP 499

  Fly   495 EDQPTPAKKKKKSKHQE 511
            ....:..||||....:|
Human   500 SISFSKPKKKKSFSKEE 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nop5	NP_477412.1	NOP5NT	2..>52	CDD:462382	15/53 (28%)
		Nop	170..397	CDD:460335	116/239 (49%)
NOP56	NP_006383.2	NOP5NT	5..70	CDD:462382	19/67 (28%)
		Nop	175..405	CDD:460335	115/238 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	458..594		26/70 (37%)