Protein Alignment Wee1 and PEK

DIOPT Version :9

• Sequence 1: NP_001260167.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_649538.1
• Gene: PEK / 40653
• FlyBaseID: FBgn0037327
• Length: 1162
• Species: Drosophila melanogaster
• Alignment Length: 591
• Identity: 109/591 - (18%)
• Similarity: 165/591 - (27%)
• Gaps: 304/591 - (51%)

  Fly   220 QAPKRLALHDTN------ISRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSS 278
            ||.:|.....|.      .|||:.:|..:..:|.|.|||||:..|:||...||||:...|...||
  Fly   617 QANQRTISESTTHSGEHYTSRFQSDFELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESS 681

  Fly   279 FEKRALNEVWAHAVLGKHDNVVRYYSAWAE----------------------------------- 308
             .:|.|.|....|.. :|.|:|||:.:|.|
  Fly   682 -RQRVLREARTLASC-EHHNIVRYFHSWTETPPTGWQEEEDRKLLAHELSTSIQIETPDDSTMPS 744

  Fly   309 ----------------------------------------------------------------- 308
                                                                             
  Fly   745 LTEQLKEKRQQQLLSWVSDAANSTACSHDFHLPGESSLKNIREEYDYDEEEDSLIEFRSESQSAA 809

  Fly   309 ----------DD-------------------------------------HMLIQNEF-------C 319
                      ||                                     |.|:.|.|       .
  Fly   810 LRAEEEDDTDDDYEEDEEQQGDHEKRHRSSVSIDIHSASFDLKNINYSQHQLVSNSFQIESVRPK 874

  Fly   320 DGGSLHAR--------------IQDH-----------------------------------CLGE 335
            ..||..|.              .|:|                                   |..|
  Fly   875 SSGSDDANDDNKARRKPLTLALAQNHNNNQNGSQPTPSSATILNGTVAKPSKVYLYIQMQLCRKE 939

  Fly   336 ---------------AELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQ 385
                           |.:..:...:::.:.|:|...|:|.||||.|||.:           |..|
  Fly   940 SLRDWLRDNRSETRAAHIGDIFHQIVDAVDYVHLKGLIHRDLKPSNIFFS-----------QDGQ 993

  Fly   386 TKDDDGMDSVYEELRHSENLVTYKIGDLGHVTSVKEPYVEEGDCRYL-PKEILHEDYSNLFKADI 449
            .|..|  ..:..::....|||. |.||...:.|......:.|...|: |:::|.:.|.  :|.||
  Fly   994 IKIGD--FGLVTDMADIPNLVA-KCGDQSGLPSCARHTQQVGTHLYMSPEQLLGQHYD--YKVDI 1053

  Fly   450 FSLGITLFEAAGGGPLPKNGPEWH--------------NLRDGKVPILPSLSRDF-------NEL 493
            :|||:..||.             |              :||||:.|      :||       .:|
  Fly  1054 YSLGLIFFEL-------------HVYFSTEMERIKTLRSLRDGQYP------KDFAVNYPQQYDL 1099

  Fly   494 IAQMMHPYPDKRPTSQSIFSHPILSAVDSKSKLQLGLELTVEKRKNEILMNKLREAKKQIKLLEQ 558
            :.||:...|::||.::.:           ||:|:..|:|.          :.|.|.:.:...|.:
  Fly  1100 LQQMLSAQPEQRPQTKQL-----------KSQLRNILQLP----------HLLSEGQSEQAELAE 1143

  Fly   559 RVNLLA 564
            |...|:
  Fly  1144 RARRLS 1149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_001260167.1	PTKc_Wee1	238..516	CDD:270953	92/517 (18%)
		Pkinase	239..515	CDD:278497	92/515 (18%)
PEK	NP_649538.1	Luminal_EIF2AK3	73..401	CDD:188874
		PKc_like	635..1113	CDD:304357	94/514 (18%)
		S_TKc	<925..1118	CDD:214567	52/238 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468139
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11042
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030