Protein Alignment Wee1 and wee2

DIOPT Version :10

• Sequence 1: NP_477035.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_001038367.1
• Gene: wee2 / 327471
• ZFINID: ZDB-GENE-030131-5682
• Length: 532
• Species: Danio rerio
• Alignment Length: 567
• Identity: 220/567 - (38%)
• Similarity: 310/567 - (54%)
• Gaps: 117/567 - (20%)

  Fly    39 ADDDFDKDTPEGASPQHPLQQRPKLSSGEEQQLDSKIGKEGGDGDVSMSPPCQKV-----RALRL 98
            :|:.||:.|.:....:.|. :.|::.....:.:           .||.|.|...:     :.|||
Zfish    27 SDNSFDEWTHKSVPLRSPC-RTPRIQRHRNRSI-----------TVSPSVPTSPIPYAAWKKLRL 79

  Fly    99 FSTPATPKTILQKSTTQCSNHLSAAAAAVNASRRSDDLFRLSERPRSLPLHNRKLPTQDTANVNP 163
            ..:|:|||::|.|||..||:         :.:.||....|||.....:|          :.|:||
Zfish    80 CDSPSTPKSLLSKSTMPCSS---------SKTCRSQRFLRLSTAFERVP----------SVNINP 125

  Fly   164 FTPDSL---MAHNKKRCRTQFGRENLNLNVNAMQKYLLSDACDDDVTEEAGDSMREIHQQA---- 221
            ||||::   ..|.|::                      |...|||  |:.|...:||...:
Zfish   126 FTPDTVRRNSEHYKRK----------------------SQRSDDD--EDYGPRSKEIQNSSEDES 166

  Fly   222 ----PKRLALHDTNISRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKR 282
                .||.|:....:||::.||:::..|||||||.|::||.|||||:||||:|::|:|||:.|:.
Zfish   167 FFLPSKRPAVSARMLSRYESEFLELACIGVGEFGSVYRCVKRLDGCMYAIKRSRRPIAGSANEQL 231

  Fly   283 ALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDGGSLH-----ARIQDHCLGEAELKIVL 342
            ||.||:||||||.|.:||||||||||||||:||||:|||||||     .|.|.......||:.:|
Zfish   232 ALKEVYAHAVLGHHPHVVRYYSAWAEDDHMIIQNEYCDGGSLHDAITEKREQGEFFSVPELRDLL 296

  Fly   343 MHVIEGLRYIHSNDLVHMDLKPENIF----STMNPNAHKLVEVQPQQTKDDDGMDSVYEELRHSE 403
            :.|..||:|||::.|||:|:||.|||    ||::...              :| ||..|:..||.
Zfish   297 LQVSMGLKYIHNSGLVHLDIKPSNIFICRRSTLSAGG--------------EG-DSEEEDESHSS 346

  Fly   404 NLVTYKIGDLGHVTSVKEPYVEEGDCRYLPKEILHEDYSNLFKADIFSLGITLFEAAGGGPLPKN 468
            .:| |||||||||||:..|.|||||.|:|..|:|.|||::|.|||||:||:|:..|||..|||:|
Zfish   347 GVV-YKIGDLGHVTSISSPQVEEGDSRFLAYEVLREDYTHLPKADIFALGLTVLLAAGASPLPQN 410

  Fly   469 GPEWHNLRDGKVPILP-SLSRDFNELIAQMMHPYPDKRPTSQSIFSHPILSAVDSKSKL--QLGL 530
            |.:||.||.|::|.|| .|...|.:|:..::.|.|..||::.::..|.:| ..:...||  ||..
Zfish   411 GDDWHRLRQGELPNLPHELPALFKDLLKSLLDPDPTARPSATALCRHDVL-CKERAGKLATQLRK 474

  Fly   531 ELTVEKRKNEILMNKLREAKKQIKLLEQRVNLLAVTN-----NPDSL 572
            ||.|||.:..:|..:|:||:            ||.|:     .|.||
Zfish   475 ELNVEKFRTAMLERELKEAR------------LAATSPQQSCQPGSL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_477035.1	PTKc_Wee1	238..516	CDD:270953	149/287 (52%)
wee2	NP_001038367.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	123..166		16/66 (24%)
		PTKc_Wee1b	187..459	CDD:271041	149/287 (52%)