Protein Alignment Wee1 and Eif2ak1

DIOPT Version :9

• Sequence 1: NP_001260167.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: XP_038945063.1
• Gene: Eif2ak1 / 27137
• RGDID: 70883
• Length: 645
• Species: Rattus norvegicus
• Alignment Length: 631
• Identity: 123/631 - (19%)
• Similarity: 193/631 - (30%)
• Gaps: 307/631 - (48%)

  Fly   137 FRLSERPRSLPLHNRKLPTQDTANVNPFTPDSLMAHNKKRCRTQFGRENLNLNVNAMQKYLLSDA 201
            |..|:...||.||:.:..|.            ||...|:|.|                    .|.
  Rat   107 FTCSDEFSSLRLHHNRAITH------------LMRSAKERVR--------------------QDP 139

  Fly   202 CDDDVTEEAGDSMREIHQQAPKRLALHDTNISRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIYA 266
            |.|:      ..|::|..   :.:|| :...||:..||.::.::|.|.:|.|::..|:|||..||
  Rat   140 CQDN------SYMQKIRS---REIAL-EAQTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQHYA 194

  Fly   267 IKKSKKPVAGSSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDHML------------------ 313
            |||.....|..:...:.|.||...|.| :|.|:|.|::||.|..|:|
  Rat   195 IKKILIKSATKTDCMKVLREVKVLAGL-QHPNIVGYHTAWIEHVHVLQPQDRVPIQLPSLEVLSE 258

  Fly   314 ------------------------------------IQNEFCDGGSLHA--------------RI 328
                                                ::||..:..|..|              .:
  Rat   259 HEGDRNQGGVKDNESSSSIIFAELTPEKENPLAESDVKNENNNLVSYRANLVIRSSSESESSIEL 323

  Fly   329 QDHCLGEAELKIVLMH------------------------------------------------- 344
            |:..|.|:.|:.|:.|
  Rat   324 QEDGLNESPLRPVVKHQLPLGHSSDVEGNFTSTDESSEDNLNLLGQTEARYHLMLHIQMQLCELS 388

  Fly   345 -----------------------------------VIEGLRYIHSNDLVHMDLK--PENIFSTMN 372
                                               ::||:.|||:..:||.|||  .|:..|...
  Rat   389 LWDWIAERNNRSRECVDEAACPYVMASVATKIFQELVEGVFYIHNMGIVHRDLKVYSESKMSVFF 453

  Fly   373 PNAHKLVEVQP--------------QQTKDDDGMDSVYEELRHSENLVTYKIGDLG--------- 414
            | .||:...||              ||.                      ||||.|
  Rat   454 P-PHKMCSSQPFICVPRNIFLHGPDQQV----------------------KIGDFGLACADIIQK 495

  Fly   415 --------------HVTSVKEPYVEEGDCRYL-PKEILHEDYSNLFKADIFSLGITLFEAAGGGP 464
                          |.:.|       |.|.|. |:::...:|.  .|:|::|||:.|.|.
  Rat   496 SADWTNRNGKGTPTHTSRV-------GTCLYASPEQLEGSEYD--AKSDMYSLGVILLEL----- 546

  Fly   465 LPKNGPEWH------NLRDGKVPILPSLSR------DFNELI-----AQMMHPYPDKRPTSQSIF 512
            ....|.|..      .:|.|::|  .|||:      .:.:|:     ||        ||::..:.
  Rat   547 FQPFGTEMERATVLTGVRTGRIP--ESLSKRCPVQAKYIQLLTGRNAAQ--------RPSALQLL 601

  Fly   513 SHPILSAVDSKSKLQLGLELTVEKRKNEILMNKLREAKKQIKLLEQ 558
            ...:.   .:...:.|.|::.:.:::.||     .|.|||:.||.|
  Rat   602 QSELF---QTTGNVNLTLQMKIMEQEKEI-----EELKKQLSLLSQ 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_001260167.1	PTKc_Wee1	238..516	CDD:270953	91/486 (19%)
		Pkinase	239..515	CDD:278497	90/484 (19%)
Eif2ak1	XP_038945063.1	STKc_EIF2AK1_HRI	160..604	CDD:270951	93/491 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930