Protein Alignment Wee1 and hri2

DIOPT Version :9

• Sequence 1: NP_001260167.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_593146.1
• Gene: hri2 / 2541943
• PomBaseID: SPAC222.07c
• Length: 639
• Species: Schizosaccharomyces pombe
• Alignment Length: 728
• Identity: 145/728 - (19%)
• Similarity: 237/728 - (32%)
• Gaps: 290/728 - (39%)

  Fly    31 FNPRKLRFADDDFDKDTPEGASPQHPLQQRPKLSSGEEQQLDSKIGKEGGDGDVSMSPPCQKVRA 95
            ||..|  .|:|....:|....|.::           |.|..|..:.|.|.          ..:.|
pombe     4 FNAHK--SAEDGNYSETTNAISLKN-----------ERQSRDLSVNKHGR----------MLLTA 45

  Fly    96 L-----RLF-STPATPKTI-------LQKSTTQCSNHLSAAAAAVNASRRSDDLFRL----SERP 143
            |     :|: :.||..|.:       |||.......::...||.  .|...|.|..|    .|..
pombe    46 LLENFCQLYDNNPAKSKRLFALICHTLQKIGILEEEYIEELAAV--RSNYQDALHHLILQAREAI 108

  Fly   144 RSLPLHNRKLPTQDTANVNPFTPDSLMAHNKKRCRTQFGRENLNLNVNAMQKYLLSDACDDDVTE 208
            |......|.|...|..||....|       ::...::|..:.||:.....:          |:|.
pombe   109 RLDDAEERLLALPDPTNVFEKFP-------QETALSKFSVDGLNVRQFRFR----------DLTL 156

  Fly   209 EAGDSMREIHQQAPKRLALHDTNISRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKP 273
            |:....|.                ||:..:|.:.:::|.|.||.|:...|::||..||:||
pombe   157 ESWLQSRN----------------SRYIEDFEEYSLLGRGGFGSVYHVRNKIDGAEYAMKK---- 201

  Fly   274 VAGSSFEKRALNEVWAH-AVLGK--HDNVVRYYSAWAE---------------DDHMLIQNEFCD 320
             ..|:|::.:.::::.. ..|.|  |.||:||:|:|.|               ...:|..:.:||
pombe   202 -INSTFQQMSYSKIFREIKCLAKMDHPNVIRYFSSWVESTTEATQMPIVMSKNSSRVLGTSSYCD 265

  Fly   321 ----------------------------------------------------------------- 320
                                                                             
pombe   266 VNGMDSIIFEPTESSALTDDILFAEDPGTESIISTSRKSSYSSTTESSNFENLESPRNLHDSNVS 330

  Fly   321 --------------------GGSLHARI------------------QDH------CLGEAELKIV 341
                                .|..|:.|                  ::|      |..:.:|...
pombe   331 TFNNTTILDDDYSSSMHISKTGPTHSFIIYIQMQLCFDDLESYLIRRNHFLSFPLCKEQIQLHTD 395

  Fly   342 LMH-VIEGLRYIHSN-DLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSV----YEELR 400
            |.. :|.|:.|:|.. :|:|.|:||.|||         |.:..|    :|.|  ||    |.:..
pombe   396 LFRMIINGVMYVHEGVNLIHRDIKPSNIF---------LAKSLP----EDRG--SVPLISYNDKN 445

  Fly   401 HSENLVTYKIGDLG-------------------HVTSVKEPYVEEGDCRYLPKEIL------HED 440
            ..:..:|.||||.|                   |:.::::.....|...|...|:|      |..
pombe   446 DLKEYITPKIGDFGLVVENKKNTETALSFLERNHLPNLQDETQHIGTATYAAPELLDAMSSQHNK 510

  Fly   441 YSNLFKADIFSLGITLFEAAGGGPLPKN---GPEWHNLRDGKVPILPSLSRDFNE-------LIA 495
            ::.  |.|.||||:.|||..  .|...|   ..:..:||.|.:|      .:|.|       ||.
pombe   511 FTK--KIDTFSLGMVLFELL--HPFQTNMERATKLQDLRRGNLP------EEFVEQHICESSLIL 565

  Fly   496 QMMHPYPDKRPTSQSIF----------SHPILSAVDSKSKLQLGLELTVEKRKNEILMNKLREAK 550
            .|....|.|||:...:.          |.|.:|.:.|.:.|.:..::       :::|::.:..:
pombe   566 WMTAKDPTKRPSLLEVLNCGLLLPNQVSMPNISNIVSTNHLDVETQM-------KLIMDENQRLR 623

  Fly   551 KQIKLLEQRVNLL 563
            :||.:|..|:..|
pombe   624 EQIAVLRSRIQHL 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_001260167.1	PTKc_Wee1	238..516	CDD:270953	91/455 (20%)
		Pkinase	239..515	CDD:278497	91/453 (20%)
hri2	NP_593146.1	STKc_EIF2AK	164..585	CDD:270898	92/466 (20%)
		S_TKc	171..583	CDD:214567	90/441 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I1626
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050