Protein Alignment Wee1 and mik1

DIOPT Version :10

• Sequence 1: NP_477035.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_595093.1
• Gene: mik1 / 2540885
• PomBaseID: SPBC660.14
• Length: 581
• Species: Schizosaccharomyces pombe
• Alignment Length: 611
• Identity: 143/611 - (23%)
• Similarity: 224/611 - (36%)
• Gaps: 177/611 - (28%)

  Fly     6 SEHEMSVTSLDSSVEL-----RSRSP-SPQVFNPRKLR---------FADDDFD----------- 44
            |.||.:.:...|.:..     ..||| :|...|.:.:|         |.:.|.|
pombe    42 SGHEENQSHKSSKLTFFKPSNTKRSPHTPMQNNAKAIRLSTTVRHGIFKNSDLDGCSKPFAFSSG 106

  Fly    45 ----KDTPEGASPQHPLQQR--PKLSSGEEQQLDSKIGK----EGG-DGDVSMSP--PCQKVRAL 96
                |...:.::|....::|  ..||:|    |.||..|    ||. ....|..|  ||:|...:
pombe   107 LKLSKKIVDASTPIDLKRKRAVTSLSTG----LLSKREKWSLWEGNLTNPRSEQPHTPCKKGTKI 167

  Fly    97 RLF--STPATPKTI----------------LQKSTTQCSNHLSAAAAAVNASRRSDDLFRLSERP 143
            :|.  .:|.:|.|.                |....:..|:.........:.|..|:||....|.|
pombe   168 KLKPPQSPLSPTTSLLARKCKHIDLDTFSRLDHPNSDSSDETFEMEELPSLSYGSEDLLEFCETP 232

  Fly   144 -RSLPL-----HNRKLPTQDTANVNPFTPDSLMAHNKKRCRTQFGRENLNLNVNAMQKYLLSDAC 202
             :|.|:     |......:|..:...:||.|                .:.||:|:.
pombe   233 CKSQPIFLSSSHVNNWDEKDVPSSLSWTPTS----------------PIFLNINSA--------- 272

  Fly   203 DDDVTEEAGDSMREIHQQAPKRLALHDTNISRFKREFMQVNVIGVGEFGVVF--QCVNRLDGCIY 265
             ||..||                   :...|..:..|.||..|...:|..|:  ..:|.....:|
pombe   273 -DDYEEE-------------------EDWTSDLRIRFQQVKPIHESDFSFVYHVSSINPPTETVY 317

  Fly   266 AIKKSKKPVAGSSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDGGSLHARIQD 330
            .:|..||..|..:.::|.|.||.....|.....||...:.|:.:|::.:|.::|:.|.|...:.:
pombe   318 VVKMLKKNAAKFTGKERHLQEVSILQRLQACPFVVNLVNVWSYNDNIFLQLDYCENGDLSLFLSE 382

  Fly   331 HCLGEAELK------IVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDD 389
              ||..::.      .:|..:.:.|.:||..:.||:|:||.|:..|.:.|
pombe   383 --LGLLQVMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGN--------------- 430

  Fly   390 DGMDSVYEELRHSENLVTYKIGDLGHVTS--VKEPYVEEGDCRYLPKEIL-HEDYSNLFKADIFS 451
                              .|:||.|..||  |......|||..|:..||| ..:|..  .||::|
pombe   431 ------------------LKLGDFGLATSLPVSSMVDLEGDRVYIAPEILASHNYGK--PADVYS 475

  Fly   452 LGITLFEAAGGGPLPKNGPEWHNLRDGKVPILPSL-----------------SRDFNELIAQMMH 499
            ||:::.|||....||:||.||..||.|....||:|                 :.....|:.:|.|
pombe   476 LGLSMIEAATNVVLPENGVEWQRLRSGDYSNLPNLKDLLLSKEKVQINKVRCAESLQCLLQRMTH 540

  Fly   500 PYPDKRPTSQSIFSHPILSAVDSKSK 525
            ||.|.|||:|.:.:.|.:..:...|:
pombe   541 PYVDCRPTTQDLLAMPEMIFISEHSQ 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_477035.1	PTKc_Wee1	238..516	CDD:270953	84/305 (28%)
mik1	NP_595093.1	PTKc_Wee1_fungi	288..556	CDD:270954	84/304 (28%)