Protein Alignment Wee1 and wee1

DIOPT Version :10

• Sequence 1: NP_477035.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_587933.1
• Gene: wee1 / 2539123
• PomBaseID: SPCC18B5.03
• Length: 877
• Species: Schizosaccharomyces pombe
• Alignment Length: 622
• Identity: 157/622 - (25%)
• Similarity: 243/622 - (39%)
• Gaps: 158/622 - (25%)

  Fly     1 MAFRQSEHEMSV-------TSLDSSVELRSRSPS----PQVFNPRKLRFADDDFDKDTPEGAS-- 52
            :.|..|:.:.:|       :|.|:|..::|..||    ||........|:|:.....:....|
pombe   288 LGFASSQTKSAVSNNHSRNSSKDASFMMKSFIPSNRSHPQTQQNESSLFSDNSMVNSSSNSFSLF 352

  Fly    53 PQHPLQQRP--KLSSGEEQQLDSKIGKEGGDGDVSMSPPCQKVRALRLFS-----------TPAT 104
            |...|...|  :|.:...||:               .||.|...:..|.|           ||..
pombe   353 PNATLPNPPSSELLTTPFQQI---------------KPPSQVFMSTGLLSKQHRPRKNINFTPLP 402

  Fly   105 PKTILQKST---TQCSNHLSAAAAAVNASRRSDDLFRLSERPRSLPLHNRKLPT-------QDTA 159
            |.|..:.||   ...|:..|..:.:..::.::|..|...|   :.|.::..:||       .|..
pombe   403 PSTPSKPSTFVRPHSSSTDSPPSPSTPSNTQTDSYFIQRE---NTPTNHNSIPTIQLEKSSMDFL 464

  Fly   160 NVNPFTPDSLM--AHN-------KKRC-----RTQFGREN-LNLNVNAMQKYLLSDACDDDVT-- 207
            ..:|  |.|.:  :||       .:||     |..|..|| ::::::..|...:....::.::
pombe   465 RFDP--PPSAVKTSHNYGLPFLSNQRCPATPTRNPFAFENTVSIHMDGRQPSPIKSRNNNQMSFA 527

  Fly   208 --EEAGDSMREIHQQAPKRLALH----------DTNISRFKREFMQVNVIGVGEFGVVFQCVNRL 260
              |||     ::.|.:.....|.          .::.|.....|..|.::|.|||..|||..:.:
pombe   528 MEEEA-----DVSQPSSSSFTLSFPSALTSSKVSSSTSHLLTRFRNVTLLGSGEFSEVFQVEDPV 587

  Fly   261 DGCI-YAIKKSKKPVAGSSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDGGSL 324
            :..: ||:||.|...:|.....|.|.||.....|..||::|....:|.....:.:|.|.|:.|||
pombe   588 EKTLKYAVKKLKVKFSGPKERNRLLQEVSIQRALKGHDHIVELMDSWEHGGFLYMQVELCENGSL 652

  Fly   325 HARIQDH----CLGEAELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQ 385
            ...:::.    .|.|..:..:|:.|..||::||..:.||:||||.|:..|.
pombe   653 DRFLEEQGQLSRLDEFRVWKILVEVALGLQFIHHKNYVHLDLKPANVMITF-------------- 703

  Fly   386 TKDDDGMDSVYEELRHSENLVTYKIGDLG--HVTSVKEPYVEEGDCRYLPKEILHEDYSNLF--K 446
                :|               |.||||.|  .|..|......||||.|:..|:|   .::|:  .
pombe   704 ----EG---------------TLKIGDFGMASVWPVPRGMEREGDCEYIAPEVL---ANHLYDKP 746

  Fly   447 ADIFSLGITLFEAAGGGPLPKNGPEWHNLRDGKVPILPSLS--------------RDFNELIAQ- 496
            |||||||||:||||....||.||..|..||.|.:...|.||              ...|.:|.|
pombe   747 ADIFSLGITVFEAAANIVLPDNGQSWQKLRSGDLSDAPRLSSTDNGSSLTSSSRETPANSIIGQG 811

  Fly   497 --------MMHPYPDKRPTSQSIFSHPILSAVDSKSK 525
                    |:.|.|..|||...|.:...:..|:.:.|
pombe   812 GLDRVVEWMLSPEPRNRPTIDQILATDEVCWVEMRRK 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_477035.1	PTKc_Wee1	238..516	CDD:270953	97/309 (31%)
wee1	NP_587933.1	PTKc_Wee1_fungi	565..838	CDD:270954	97/308 (31%)